促红细胞生成素及其受体对多种疾病的影响  

Erythropoietin and its receptors on the influence of various diseases

作　　者：王丽娜 呼格吉乐[2] 兰海霞[3] 

机构地区：[1]内蒙古医科大学,内蒙古呼和浩特010059 [2]内蒙古医科大学附属医院检验科 [3]解放军第253医院儿科

出　　处：《疾病监测与控制》2017年第12期968-969,共2页Journal of Diseases Monitor and Control

基　　金：内蒙古医科大学科技百万工程项目(YKD2016KJBW(LH)008内蒙古自治区科技计划项目[2017])

摘　　要：促红细胞生成素(Erythropoietin EPO)主要是由肾脏球旁细胞分泌的一种细胞因子,本质为糖蛋白激素,其主要功能是促进骨髄内造血及红系细胞的分化和增殖,并可促进红细胞的成熟。目前临床上EPO主要用于早产儿贫血疾病、新生儿缺血缺氧性脑病、神经系统疾病、肾脏疾病、心脏疾病、肿瘤类等疾病的治疗。但有一定的分岐。因此本研究对EPO的生物特性及其在临床中对多种疾病治疗过程中的影响进行综述。Erythropoietin （EPO） is a kind of cytokine secreted by renal parietal cells, which is essentially glycoprotein hormone. Its main function is to promote the differentiation and proliferation of hematopoietic and erythroid cells in bone marrow and promote the maturation of red blood cells. At present, EPO is mainly used for the treatment of preterm infants with anemia, neonatal hypoxic ischemic encephalopathy, nervous system diseases, kidney diseases, heart diseases, cancer and other disases. But there is a certain divergence. Therefore, this article on the biological characteristics of EPO and its clinical treatment of a variety of diseases are reviewed.

关 键 词：促红细胞生成素促 红细胞生成素受体 新生儿缺血缺氧性脑病 肿瘤 

分 类 号：R318.12[医药卫生—生物医学工程]