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机构地区:[1]山西省肿瘤医院山西医科大学附属肿瘤医院消化外科微创中心,太原030013
出 处:《中国药物与临床》2017年第12期1746-1748,共3页Chinese Remedies & Clinics
基 金:山西省科技厅攻关项目(20150313007-7)
摘 要:目的探索全胃切除术后营养支持的最佳模式。方法对全胃切除术后患者随机进行肠内序贯营养(PN+EN)、早期肠内营养(TEN)、全肠外营养(TPN)方案营养支持,对比3组患者术后营养指标和并发症等。结果 PN+EN患者营养指标恢复较好;TPN组患者费用高且术后对肝功能影响较大;TEN组发生腹痛、腹胀、一过性肠梗阻的并发症高于其余2组。结论恰当的PN+EN治疗是全胃切除术后患者最佳营养治疗方案。Objective To explore for the optimal modality of nutritional support after total gastrectomy. Methods Following total gastrectomy, the patients were randomized to receive different nutritional support regimens: se-quential parenteral and enteral nutritional(PN +EN), early total enteral nutrition(TEN) and total parenteral nutrition(TPN). The nutritional indices and complications in the three groups were compared. Results The patients on PN+EN showed better nutritional indices. The patients on TPN suffered higher medical cost and greater impairment of liv-er function. Those on TEN experienced more complications including abdominal pain, distension, and transient bowel obstruction compared with the other two groups. Conclusion Proper use of PN+EN may be the optimal nutritional therapy for patients after total gastrectomy.
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