出 处:《山西医药杂志》2017年第24期2979-2982,共4页Shanxi Medical Journal
基 金:石家庄市科技指导计划项目(151460983)
摘 要:目的探讨认知介入干预对孕中晚期乙型肝炎患者认知行为、遵医嘱及阻断乙型肝炎病毒(HBV)母婴传播效果的影响。方法回顾性选取我院产检、住院及顺利分娩的124例,合并HBV感染的孕中晚期孕妇及其分娩的新生儿的临床资料,按住院顺序单双号分为对照组和观察组各62例。均主张予乙型肝炎免疫球蛋白治疗,对照组行常规健康教育,观察组实施全程规范性认知介入干预。采用自拟相关问卷评估2组孕妇认知行为、用药依从性、遵医嘱情况,于婴儿出生时、2岁及5岁时行HBV-DNA检测乙肝表面抗体(HBsAb)阳转率和乙肝表面抗原(HBsAg)阳性率。结果 2组护理干预前抗HBV知识认知程度比较差异无统计学意义(P>0.05),干预后观察组抗HBV知识认知水平整体高于对照组,差异有统计学意义(P<0.05)。护理干预后观察组用药依从性和遵医嘱情况均优于对照组,其中观察组坚持用药率、遵医嘱良好率依次为75.8%、83.9%显著高于对照组56.4%、62.9%(P<0.05)。观察组婴儿出生时、2岁及5岁时HBsAb阳转率均明显高于对照组,而HBsAg阳性率均明显低于对照组,2组HBV母婴传播阻断效果比较差异有统计学意义(P<0.05)。结论对合并HBV感染的孕中晚期孕妇实施全程规范性认知介入干预可显著提高其抗HBV知识认知水平和用药依从性,促进遵医嘱行为,从而有助于增强阻断HBV母婴传播效果。Objective To explore the effects of cognitive intervention on the cognitive behaviors ,following the doctor′s advice and interruption of hepatitis B virus (HBV) mother-to-child transmission in patients with hepa-titis B in the second and third trimesterof pregnancy. Methods The clinical data of 124 pregnant women with HBV infection in the second and third trimester of pregnancy having prenatal care ,hospitalized and delivering smoothly in our hospital and the clinical data of their neonates were retrospectively selected .According to the odd and even numbers of hospitalization order ,they were divided into the control group ( n=62) and the observation group ( n=62) .All patients were treated with hepatitis B immunoglobulin .The control group was given the rou-tine health education ,and the observation group was given the whole-course standardized cognitive intervention . The cognitive behaviors ,medication compliance and status of following the doctor′s advice of pregnant women in the two groups were evaluated by the self-maderelated questionnaires ,and the HBV-DNA assay was performed to detect the HBsAb positive conversion rate and the HBsAg positive rate when the baby was born ,2 years old and 5 years old ,respectively .Results There was no significant difference in the cognition degree of anti-HBV knowl-edge between the two groups before nursing intervention ( P〉0 .05) .After intervention ,the cognition level of anti-HBV knowledge in the observation group on the whole was higher than that in the control group ( P〈0 .05) . After nursing intervention ,medication compliance and status of following the doctor′s advice in the observation group were better than those in the control group ,and the medication compliance rate and good rate of following the doctor′s advice were higher in the observation group than those in the control group (75.8% vs 56.4% ;83.9% vs 62.9% ) ( P 〈0.05) .When the baby was born ,2 years old and 5 years old ,the HBsAb positive con-version rate was s
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