经颅多普勒超声仪监测微栓子技术在脑梗死患者中的临床应用  

The Clinical Application of Microemboli Monitored by Cranial Doppler Ultrasonography in Patients with Cerebral Infarction

作　　者：王雷[1] 康彩英 于彩敏[1] 

机构地区：[1]定州市人民医院,河北省定州市建设街073000 [2]定州市妇幼保健院,河北省定州市中山中路073000

出　　处：《中国数字医学》2017年第12期51-53,共3页China Digital Medicine

基　　金：河北省卫生厅课题-应用多普勒超声监测脑炎患者微栓子的临床研究(编号:20171500)~~

摘　　要：目的:探讨经颅多普勒超声仪监测微栓子技术的在脑梗死患者中的临床应用。方法:选取脑梗死患者120例,经微栓子技术监测阳性病例62例(观察组),阴性病例58例(对照组)。结果:两组合并症、吸烟饮酒史、监测距治疗时间、C反应蛋白和血清白细胞水平等比较,无统计学差异(P>0.05);血糖、尿酸和总胆固醇等血液指标比较,有统计学差异(P<0.05);观察组NIHSS、ESSEN评分和半年内脑梗死发生率均高于对照组,差异具有统计学意义(P<0.05);两组脑梗死不同亚型比较,除大动脉粥样硬化型(L从)、其他明确原因(SOE)两型外,另外三型比较均有统计学意义(P<0.05)。结论:经颅多普勒超声仪监测微栓子技术用于脑梗死病理诊断,可明确患者的神经功能缺损情况,评估脑梗死的发生风险,进行病源分型;对疾病的预防、治疗和预后有积极意义。Objective： To explore the clinical application of transcraniaI Doppler ultrasonography in the monitoring of microembolization in patients with cerebral infarction. Methods： Choose 120 cases of patients with cerebral infarction, the micro embolus technology monitoring positive cases 62 cases （observation group）, the negative cases, 58 cases （control group）. Results： Two groups of complications, smoking, alcohol, monitoring of treatment time, c-reactive protein and serum levels of white blood cells, no statistical difference （P〉0.05）; Blood glucose, total cholesterol and uric acid blood index comparison, stadsticaUy significant （P〈 0.05）; Observation group NIHSS, essen-based score and the incidence of cerebral infarction were higher than control group in half year, statistically significant difference （P〈0.05）; Two groups of comparing different subtypes of cerebral infarction, in addition to the artery atherosclerosis （LAA）, other specific reasons （SOE） two type, three other model more have statistical significance （P〈0.05）.Conclusions： Transcranial doppler ultrasound instrument monitoring micro embolus technology used in cerebral infarction pathological diagnosis, can clear the patient＇s neurologic deficits, risk assessment of cerebral infarction, to cause classification; For the prevention, treatment and prognosis of disease has a positive meaning.

关 键 词：经颅多普勒超声 微栓子技术 脑梗死 应用 

分 类 号：R319[医药卫生—基础医学] R540.4