止遗方联合艾灸治疗下焦虚寒型小儿遗尿症临床研究  

Clinical Effect of Preventing Enuresis Prescription Combined With Moxibustion on Children with Nocturnal Enuresis of Lower Jiao Deficient Cold Type

作　　者：孙凤平 韩雪 葛国岚 

机构地区：[1]河南省儿童医院,河南郑州450053

出　　处：《中医学报》2017年第12期2565-2568,共4页Acta Chinese Medicine

基　　金：河南省重点中医专科建设项目(4-019)

摘　　要：目的:观察止遗方联合艾灸治疗下焦虚寒型小儿遗尿症(nocturnalenuresis,NE)的临床疗效。方法:80例NE患儿随机分为观察组和对照组各40例。观察组给予止遗方免煎颗粒口服,每天2次,联合艾灸关元、中极、足三里、三阴交等穴位,每天1次;对照组给予醋酸去氨加压素(弥凝片)睡前口服,每次0.2 mg,赖氨肌醇维生素B12口服液,每次10 m L,每天2次。连续治疗1个月,随访6个月。观察两组患儿临床疗效、血清维生素B12和抗利尿激素(antidiuretic hormone,ADH)水平,并比较治疗过程中不良反应和治疗后复发情况。结果:观察组有效率显著优于对照组(P<0.05),两组患儿治疗前后血清维生素B12水平比较有显著性差异(P<0.05),两组比较,差异无统计学意义(P>0.05);治疗后观察组患儿血清ADH高于对照组,两组比较,差异有统计学意义(P<0.05);观察组不良反应率、复发率显著低于对照组(P<0.01)。结论:止遗方联合艾灸治疗NE疗效确切,不良反应率和复发率低。Objective： To observe the clinical effect of Preventing Enuresis prescription combined with moxibustion on children with nocturnal enuresis（ NE） of lower Jiao deficient cold type. Methods： 80 NE children were randomly divided into the observation group and the control group with 40 cases in each group. The observation group were treated with preventing Enuresis prescription orally twice per day,combining with moxibustion Guanyuan（ RN4）,Zhongji（ RN3）,Zusanli（ ST36）,Sanyinjiao（ SP6） and so on once per day. The control group were treated with Desmopressin acetate tablets（ Minirin） orally before sleeping,0. 2 mg once,as well as Lai ammonia inositol vitamin B12 oral liquid,10 mL once,twice per day. Continuous treatment of 1 month and followed up for 6 months. The clinical efficiency,serum vitamin B12（ VitB 12） and antidiuretic hormone（ ADH） levels was compared as well as adverse reactions during treatment and recurrence after treatment. Results： The effective rate of observation group was higher than that in the control group（ P〈0. 05）. Within the two groups there are significant differences concerned as serum VitB 12 level（ P〈0. 05）,but no significant differences between the two groups（ P〈0. 05）. Serum ADH level in the control group is higher than the control group after treatment group and there is statistically significance（ P〈0. 05）. The number of adverse reactions and recurrence in the observation group was lower than that in the control group（ P〈0. 01）. Conclusion： The efficacy of Preventing Enuresis prescription combined with moxibustion for treating NE is accurate,with low recurrence and adverse reactions.

关 键 词：小儿遗尿症 下焦虚寒证 止遗方 艾灸 

分 类 号：R272.6[医药卫生—中医儿科学]