含漏芦方剂主治病证的用药规律分析  

Analysis on Medication Rules of Formulae Containing Rhapontici Radix

作　　者：栗圣榕 夏厚林 涂翔 胡攀 李洋 李文婷 刘娟 邓曦 张廷模 

机构地区：[1]成都中医药大学药学院中药材标准化教育部重点实验室四川省中药资源系统研究与开发利用重点实验室——省部共建国家重点实验室培育基地 [2]成都中医药大学附属医院 [3]成都中草药研究所

出　　处：《中国实验方剂学杂志》2018年第2期192-199,共8页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：四川省科技厅科技支撑计划项目(2015SZ0038)

摘　　要：目的：应用MatlabR2013a软件对《中医方剂大辞典》中含漏芦的方剂进行分析，为指导临床用药、扩大漏芦使用范围提供依据。方法：收集整理《中医方剂大辞典》中包含漏芦的方剂，按特定格式录入软件中，按时期和主治疾病进行对应分析、加权秩和比综合评价和关联分析，分析漏芦运用的时代特点和用药规律。结果：共收集相关方剂287首，漏芦治疗疮疡类疾病常与大黄、升麻等配伍，找出58个常用药组；治疗缺乳常与栝楼配伍，找出23个常用药组；治疗皮肤病类疾病常与刺蒺藜、玄参等配伍，找出38个常用药组。以上配伍沿用稳定、专属性强；药组用药集中，用药思路明晰。结论：《中医方剂大辞典》中含漏芦的方剂用药特点明确，分析含漏芦方剂在不同时期与不同主治时的用药规律和特点，对该药物的现代临床应用有一定的指导意义。Objective： Matlab R2013a was adopted to analyze the composition principles of formulae containing Rhapontici Radix in Dictionary of Chinese Medicine Prescription, and to provide a basis for clinical medication of Rhapontici Radix and expand its range of application. Method： To collect data of the prescription containing Rhapontici Radix in Dictionary of Chinese Medicine Prescription, logging the data in the software of Matlab R2013a by specified format, the methods of correspondence analysis, weighted rank-sum ratio （WRSR） comprehensive evaluation and correlation analysis were used to analyze the time characteristics and composition principles of Rhapontici Radix in application. Result： The database recorded a total of 287 formulae. We found 58 common compositions to treat sore and ulcer, it often mixed with Rhei Radix et Rhizoma, Cimicifugae Rhizoma and so on ; and found 23 common compositions to treat hypogalactia, it often mixed with Trichosanthis Fructus ; and found 38 common compositions to treat dermatosis, it often mixed with Tribulus terrestris, Scrophulariae Radux and so on. The using of common compositions was stable and especial, the formulae were reasonable. Conclusion： Dictionary of Chinese Medicine Prescription has a wide range of compatible drugs for Rhapontici Radix. The characteristics of treatment are clear. The assay has reflected the different characteristics in different periods and indications. It has a certain of guiding significance for modern clinical of Rhapontici Radix.

关 键 词：漏芦 方剂 配伍关系 《中医方剂大辞典》 秩和比 对应分析 关联分析 

分 类 号：R289[医药卫生—方剂学] R282[医药卫生—中药学]