血管性痴呆中医发病机制现代研究述要  

Review of modern research on pathogenesis of TCM of vascular dementia

作　　者：马青[1] 唐民科[1] 孙文燕[1] 

机构地区：[1]北京中医药大学中药学院,北京102488

出　　处：《中华中医药杂志》2018年第1期212-215,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金："重大新药创制"国家科技重大专项(No.2011ZX09201-201-22)~~

摘　　要：血管性痴呆属于中医"呆病"范畴,由于多发于中风之后,又称为"中风后痴呆"。又因具有可预防性和可治疗性,也被称为"可逆性痴呆"。中医认为其病理基础为肾精亏虚,痰瘀互结,久滞不化,阻滞络脉,酿生浊毒,败坏脑络。研究表明,发病机制中的三大要素肾虚、痰浊、瘀血与现代研究中的神经干细胞再生、炎性反应以及脂质代谢异常有密切关系。文章通过论述VD的中医发病机制与现代研究之间的相互关系,为其寻找有效的治疗方案提供新的依据及研究思路。Vascular dementia （VD） belongs to the category of ＇dullness disease＇ of TCM, also known as ＇dementia after apoplexy＇ because it often occur in back of apoplexy, and due to its preventable and treatable, it also can be called ＇reversible dementia＇. TCM thinks that pathological basis of VD is deficiency of kidney essence, intermin-gled phlegm and blood stasis, long stagnation with no change, blockade of the collateral, production of the turbid toxicity, corruption of the brain collateral. Studies shows that here has relationship between the three major factors in the pathogenesis of kidney deficiency, phlegm, blood stasis and modem research in neural stem cell regeneration, inflammatory reaction and lipid metabolism. This paper provides a new basis and research ideas for VD＇s effective treatment through discussing the relationship between the pathogenesis of VD and modem research.

关 键 词：血管性痴呆 中医发病机制 现代研究 

分 类 号：R277.7[医药卫生—中医学]