临床药师运用Roussel Uclaf因果关系评价法诊治赖氨匹林致幼儿严重肝损害1例  

Clinical Pharmacist Apply Roussel Uclaf Causality Assessment Method to Join in a Case of Children Severe Liver Injury Caused By Aspirin-DL-Lysine

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作  者:彭敏[1] 邓楠[1] 邓银华[1] 

机构地区:[1]湖南省人民医院,湖南长沙410005

出  处:《儿科药学杂志》2018年第1期40-43,共4页Journal of Pediatric Pharmacy

摘  要:目的:探讨临床药师在药物性肝损害因果分析及治疗中的作用。方法:临床药师参与1例赖氨匹林注射液致严重药物性肝损害的治疗过程,运用Roussel Uclaf因果关系评价法对肝损害与赖氨匹林的因果关系进行评估,根据相关文献与临床医师共同制定个体化给药方案。结果:临床药师参与治疗后,患儿肝功能生化指标明显下降,病情得到控制。结论:临床药师为患者提供个体化药学服务,有利于促进临床用药安全、合理。Objective: To discuss the role of clinical pharmacists in the cause analysis and treatment of drug-induced liver injury.Methods: Clinical pharmacists participated in the treatment process of severe drug-induced liver injury. The causal relationship of liver damage and the aspirin-DL-lysine was evaluated by the amount of Roussel Uclaf causality assessment method scale. According to the related literature,the individualized drug delivery scheme was formulated by clinical pharmacists and clinicists. Results: The children's biochemical indexes of liver function decreased obviously,and the condition of the disease was controlled after clinical pharmacists participated in the treatment. Conclusion: Individualized pharmaceutical care for patients provided by clinical pharmacists is conducive to the promotion of safe and rational clinical medication.

关 键 词:赖氨匹林 不良反应 药物性肝损害 Roussel Uclaf因果关系评价法 

分 类 号:R969.3[医药卫生—药理学]

 

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