一期病灶清除联合抗生素骨水泥填塞旷置术治疗慢性骨髓炎  

One stage focus clearance combined with antibiotic bone cement filling exclusion for the treatment of chronic osteomyelitis

作　　者：陈校明 刘忠 唐新桥 蒋锐中 赵紫敬 

机构地区：[1]湘潭市中心医院骨科,湖南湘潭411100

出　　处：《临床骨科杂志》2017年第6期701-703,共3页Journal of Clinical Orthopaedics

摘　　要：目的探讨一期病灶清除联合抗生素骨水泥填塞旷置术治疗慢性骨髓炎的临床疗效。方法对17例慢性骨髓炎患者采用一期病灶清除联合抗生素骨水泥填塞旷置术治疗。结果 17例感染均得到有效控制。患者均获得随访,时间12~54个月。抗生素骨水泥填塞旷置时间4~38个月。切口延迟愈合1例。随访期间未见明显肝、肾功能异常,无医源性骨折、感染复发、骨水泥植入综合征、毒性反应和过敏反应发生。结论一期病灶清除联合抗生素骨水泥填塞旷置术是治疗慢性骨髓炎的一种安全有效的手术方法。Objective To investigate the clinical effect of one stage focus clearance combined with antibiotic bone cement filling exclusion for the treatment of chronic osteomyelitis.Methods Seventeen cases with chronic osteomyelitis were treated by one stage focus clearance combined with antibiotic bone cement filling exclusion.Results Infections were effectively controlled.The 17 cases were followed up from 12 months to 54 months.Antibiotic bone cement filling exclusion time ranged from 4 months to 38 months.There was 1 case delayed healing of incision,no obvious liver and renal dysfunction occurred during the follow-up,there was not iatrogenic fracture,infection recurrence,bone cement implantation syndrome,toxic reaction and allergic reaction.Conclusions It is a safe and effective technique to treat chronic osteomyelitis with one stage focus clearance combined with antibiotic bone cement filling exclusion.

关 键 词：病灶清除 抗生素骨水泥 填塞 旷置 慢性骨髓炎 

分 类 号：R681.2[医药卫生—骨科学] R687.3[医药卫生—外科学]