碱催化2-吲哚酮合成吲哚醌  

Base-Catalyzed Synthesis of Isatin From 2-Oxindole

作　　者：宋璐娜 于静文[1] 

机构地区：[1]山西医科大学晋祠学院,山西太原030025

出　　处：《忻州师范学院学报》2017年第5期6-9,共4页Journal of Xinzhou Teachers University

基　　金：山西医科大学校级科研基金项目(02201540)

摘　　要：文章论述了一种以2-吲哚酮为底物,碳酸钾作催化剂,在氧气的作用下合成吲哚醌的新方法。该方法以操作简便、催化剂用量低(5 mol%)、无需添加任何化学计量的氧化剂以及反应条件温和为特色,特别是反应中氧气的引入使得这种方法更加绿色和实用。产物的结构通过核磁共振氢谱、核磁共振碳谱进行了表征。This paper has disclosed a novel method for the aerobic synthesis of isatin from 2-oxindole catalyzed by potassium carbonate. The approach features simple operation,low catalyst loading（ as low as 5 mol%）,no addition of any other stoichiometric oxidant and mild conditions. In particular,molecular oxygen is employed as a reagent,thus making this approach green and practical. The structure of product were characterized by ~1H NMR spectra and ^（13）C NMR spectra.

关 键 词：合成方法 氧化 吲哚醌 2-吲哚酮 碱 

分 类 号：O62[理学—有机化学]