绝经妇女良性阵发性位置性眩晕与骨密度变化的相关性分析  

Correlation analysis between benign paroxysmal positional vertigo and bone mineral density in menopausal women

作　　者：林细康[1] 金静君 季晓林[1] 叶华[1] 严金柱[1] 陈洁琼[1] 张国来[1] 王坤 刘慎敏 

机构地区：[1]福建省级机关医院福建卫生职业技术学院附属医院神经内科,福建福州350003 [2]福建省医学科学研究院,福建福州350000

出　　处：《中国耳鼻咽喉头颈外科》2017年第12期617-619,共3页Chinese Archives of Otolaryngology-Head and Neck Surgery

基　　金：福建省医学创新课题资助项目(2015-CX-13)

摘　　要：目的探讨绝经妇女良性阵发性位置性眩晕(BPPV)与骨密度(bone mineral density,BMD)变化的相关性。方法随机选取50例年龄50~80岁原发性BPPV(idiopathic BPPV,iBPPV)绝经妇女作为病例组,选取同年龄段本院体检中心绝经后健康体检者为对照组,采用双能X线吸收法分别对腰椎正位(L1~L4)及股骨颈进行测量,测量结果以T值表示。将病例组和对照组分成3个年龄段,分别对3个年龄段的T值进行统计学分析。结果病例组3个年龄段T值与对照组比较,差异均有统计学意义(t分别为-3.68、-5.98和-3.33,P均<0.05),Pearson相关性分析显示iBPPV与BMD存在负相关性(r=-0.496,P<0.05)。结论绝经妇女iBPPV与BMD变化存在相关性,研究结果对iBPPV诊断、治疗、预后评定和预防具有一定指导意义。OBJECTIVE To investigate the correlation between benign paroxysmal positional vertigo （BPPV） and bone mineral density （BMD） in menopausal women with BPPV, METHODS 50 patients between the ages of 50-80 years old of menopausal women with Idiopathic benign paroxysmal positional vertigo（iBPPV） as case group, and postmenopausal healthy people of same age doing physical examinations in hospital medical examination center were selected as control group. The lumbar spine（L1-L4） and femoral neck were measured respectively using dual energy X-ray absorptiometry and expressed in T value. The case group and the control group were divided into three age groups, and the T values of three age groups were statistically analyzed. RESULTS There was significant correlation between the ease group and control group（The t values are -3.68, -5.98 and -3.33, respectively, P〈0.05）. Pearson correlation analysis showed that there was a negative correlation between iBPPV and bone mineral density（BMD） （r=-0.496, P〈0.05）. CONCLUSION There was a correlation between benign paroxysmal positional vertigo and BMD in menopausal women. The results of this study may be helpful for the diagnosis, treatment, prognosis and precaution of iBPPV.

关 键 词：眩晕 半规管 绝经期 妇女 骨密度 良性阵发性位置性眩晕 

分 类 号：R764.3[医药卫生—耳鼻咽喉科]