Formin' bridges between microtubules and actin filaments in axonal growth cones  

作　　者：István Foldi Szilárd Szikora József Mihály 

机构地区：[1]Institute of Genetics, Biological Research Centre, HungarianAcademy of Sciences, MTA-SZBK NAP B Axon Growth andRegeneration Group, Szeged, Hungary

出　　处：《Neural Regeneration Research》2017年第12期1971-1973,共3页中国神经再生研究（英文版）

基　　金：supported by the Hungarian Science Foundation(OTKA)(K109330 to JM);the Hungarian Brain Research Program(KTIA_NAP_13-2-2014-0007 to JM);the National Research,Development and Innovation Office(GINOP-2.3.2-15-2016-00001 and GINOP-2.3.2-15-2016-00032 to JM);by an MTA Postdoctoral Fellowship(to IF)

摘　　要：It is well established that guidance of axons during neuronal development is regulated by a variety of extracellular signals,governing cytoskeletal dynamics in growth cones.The actin and microtubule（MT）cytoskeleton have both been shown to play important roles.However,a growing body of work suggests that a critical issue is the proper coordination of changes within these two major cytoskeletal systems（reviewed in Cammara-ta et al., 2016）.It is well established that guidance of axons during neuronal development is regulated by a variety of extracellular signals,governing cytoskeletal dynamics in growth cones.The actin and microtubule（MT）cytoskeleton have both been shown to play important roles.However,a growing body of work suggests that a critical issue is the proper coordination of changes within these two major cytoskeletal systems（reviewed in Cammara-ta et al., 2016）.

关 键 词：Formin＇＇ bridges axonal growth cones 

分 类 号：R3[医药卫生—基础医学]