中药对肠道黏膜免疫保护的影响及其意义  

Immunoprotective effect of traditional Chinese medicine on intestinal mucosa

作　　者：龙承星 郭艳芳[2] 刘娅薇 彭昕欣[2] 谭周进 

机构地区：[1]湖南中医药大学微生物教研室,湖南省长沙市410208 [2]湖南中医药大学第一附属医院儿科,湖南省长沙市410007

出　　处：《世界华人消化杂志》2017年第35期3115-3122,共8页World Chinese Journal of Digestology

基　　金：国家自然科学基金资助项目;No.81573951~~

摘　　要：肠道黏膜表面面积大,直接与外界抗原接触,也是接触微生物最多的部位.大量研究表明,肠道黏膜与多种疾病具有相关性.中药成分复杂,含多种生物活性成分和营养成分,能为黏膜结构完整性的维持和各项生理功能的实现提供能量和营养;能直接或间接调节肠道菌群,建立肠道黏膜免疫和屏障,治疗肠黏膜免疫的相关疾病.中医传统方药对肠道黏膜具有保护和修复作用.本文总结了中药对肠道黏膜结构、免疫、菌群和代谢的影响情况,为中药治疗肠道疾病的科学性提供依据.The intestinal mucosa has a large surface area, contacts with the external antigens directly, and is the part exposed to most microbes. Growing evidence indicates that the relationship between intestinal mucosa and diseases is close. Traditional Chinese medicine is rich in a variety of bioactive ingredients and nutrients, which can provide energy and nutrition to maintain mucosal structure integrity and realize its physiological function, regulate intestinal flora directly or indirectly, establish intestinal mucosal immunity and barrier, and treat intestinal mucosal immune-related diseases. In this paper, we summarize the effect of traditional Chinese medicine on intestinal mucosal structure, immunity, flora, and metabolism, with an aim to provide some clues to the treatment of intestinal diseases using traditional Chinese medicine.

关 键 词：中药 肠道黏膜 肠道菌群 免疫 

分 类 号：R285.5[医药卫生—中药学]