探讨子宫内膜厚度对激素治疗围绝经期功血的应用  

Investigation on application of endometrial thickness on perimenopausal dysfunctional uterine bleeding during hormone therapy

作　　者：王淼 

机构地区：[1]辽宁省开原市妇幼保健院,112300

出　　处：《中国现代药物应用》2018年第1期22-23,共2页Chinese Journal of Modern Drug Application

摘　　要：目的对围绝经期功能失调性子宫出血(功血)患者接受激素治疗时使用子宫内膜厚度测量方式指导激素治疗的作用。方法 100例围绝经期功血患者,根据指导激素治疗方法不同分为研究组和对照组,各50例。研究组根据B超检测子宫内膜厚度指导激素治疗,对照组凭经验使用激素治疗。比较两组治疗前后卵泡刺激素(FSH)、雌二醇(E2)、黄体生成素(LH)指标以及调经成功率。结果治疗前,两组FSH、E2、LH比较差异无统计学意义(P>0.05);治疗后,两组FSH、E2、LH均较治疗前改善,且研究组改善程度优于对照组,差异具有统计学意义(P<0.05)。对照组治疗显效22例,有效18例,无效10例,调经成功率为80%;研究组治疗显效27例,有效20例,无效3例,调经成功率为94%;研究组患者调经成功率高于对照组患者,差异具有统计学意义(P<0.05)。结论围绝经期功血患者接受B超检测子宫内膜厚度进行激素治疗的效果突出,可以推广使用。Objective To investigate the effect of endometrial thickness measurement for guidance of hormone therapy on patients with perimenopausal dysfunctional uterine bleeding during hormone therapy. Methods A total of 100 patients with perimenopausal dysfunctional uterine bleeding were divided by different methods of guiding hormone therapy into research group and control group, with 50 cases in each group. The research group received hormone therapy by detecting endometrial thickness with B-mode ultrasonography, and the control group received hormone therapy by experience. Comparison were made on follicle stimulating hormone（FSH）, estradiol（E2） and luteinizing hormone（LH） index before and after the treatment and the success rate of menstruation between two groups. Results Before treatment, both groups had no statistically significant difference in FSH, E2, LH（P〉0.05）. After treatment, both groups had better FSH, E2, LH than before treatment, and the research group had better improvement degree than the control group. Their difference was statistically significant（P〈0.05）. The control group had 22 excellent cases, 18 effective cases and 10 ineffective cases with success rate of menstruation as 80%, while the research group had 27 excellent cases, 20 effective cases and 3 ineffective cases, with success rate of menstruation as 94%. The research group had higher success rate of menstruation than the control group, and the difference was statistically significant（P〈0.05）. Conclusion Hormone therapy under the guidance of endometrial thickness by B-mode ultrasonography shows remarkable effect in treating patients with perimenopausal dysfunctional uterine bleeding, and can be promoted and used.

关 键 词：子宫内膜厚度 激素 围绝经期 功能失调性子宫出血 

分 类 号：R711.52[医药卫生—妇产科学]