改良纤维蛋白脂肪复合物治疗瘢痕性凹陷的临床观察  

Application of modified autologous purification of fat granules combined with platelet-rich fibrin transplantation injection in the treatment of cicatricial depress deformity

作　　者：李明[1] 李泽华[1] 陈佳[2] 顾斌[3] 谢红炬[1] 

机构地区：[1]南华大学附属第一医院医疗美容科,衡阳421001 [2]中南大学湘雅附三医院烧伤整形科,长沙410013 [3]上海交通大学医学院附属第九人民医院整复外科,上海200011

出　　处：《重庆医科大学学报》2017年第12期1570-1572,共3页Journal of Chongqing Medical University

基　　金：湖南省自然科学基金资助项目(编号:2015JJ6100)

摘　　要：目的:探讨应用改良自体纯化脂肪颗粒复合富血小板纤维蛋白(platelet-rich fibrin,PRF)注射移植对面部瘢痕性凹陷畸形进行修复的手术方法。方法:对27例面部凹陷畸形患者,取自体脂肪经离心纯化,复合PRF,瘢痕粘连松解,局部注射填充。结果:患者术后局部畸形矫正满意,术区几乎无新增瘢痕,并且原有瘢痕质地有一定程度改善,脂肪供区无并发症发生。27例均获随访,随访时间6个月至2年,效果满意,无局部硬结、感染、脂肪液化。结论:应用改良富血小板纤维蛋白复合自体脂肪,能有效提高脂肪的成活率,减少移植后液化、坏死,是修复面部瘢痕性凹陷畸形的有效方法,在临床值得推广。Objective：To explore the surgical technique of modified autologous purification of fat granule combined with platelet-rich fibrin in the treatment of facial cicatricial depress deformity.Methods：The fat granules was harvested by liposuction form 27 cases of facial cicatricial depress deformity.The scar adhesion was released;then the fat combined with platelet-rich fibrin were injected back to facial depression for filling and augmentation after centrifugal purification.Results：Totally 27 cases were involved and satisfactory results were received with no new cicatricle being observed.Original cicatricle texture was improved to a certain extent without complication occur.Post-operative follow up was conducted in 27 patients for 6 to 24 months;all patients got satisfactory results without localized indurations,infection or fat liquefaction.Conclusion ：Transplantation of modified autologous purification of fat granules combined with platelet-rich fibrin is a good method to repair facial cicatricial depress deformity,and worth promoting in the clinical.

关 键 词：富血小板纤维蛋白 自体纯化脂肪 瘢痕性凹陷畸形 移植 

分 类 号：R622.9[医药卫生—整形外科]