心脏直视手术切口皮肤病原菌分布及耐药性分析  

Distribution and drug resistance of skin pathogens in open heart surgery

作　　者：黄宇昂 孔祥[1] 林敏[1] 阮鹏[1] 

机构地区：[1]安徽医科大学第一附属医院心脏大血管外科,安徽合肥230032

出　　处：《安徽卫生职业技术学院学报》2017年第6期26-27,29,共3页Journal of Anhui Health Vocational & Technical College

摘　　要：目的:分析心脏直视手术切口致病菌的种类及耐药性,为进一步控制术后感染提供帮助。方法:分析56例心脏直视手术患者的资料。结果:24例患者(42.9%)培养出细菌,共计32株,其中革兰阳性球菌占87.50%,革兰阴性杆菌占9.375%,真菌占3.125%。革兰阳性球菌对于青霉素类、头孢类、红霉素、克林霉素耐药率均>50%,对于利奈唑胺、万古霉素耐药率为0。革兰阴性杆菌对于三代头孢类耐药率>50%,对于碳青霉烯类、喹诺酮类耐药率较低。真菌普遍耐药率不高。结论:当前心脏直视手术常规预防使用的头孢类抗生素耐药率不佳,预防术后切口感染需考虑多方面影响因素。Objective：This study was designed to provide strategy for further control of postoperative infection by analyzing the pathogens and drug resistance of incision pathogens in open heart surgery.Methods：The clinical data of 56 patients undergoing open heart surgery was analyzed.Results：32 species of bacteria were found in 24 cases （42.9%）, of which gram positive cocci accounted for 87.50%, gram negative bacilli accounted for 9.375%, fungi accounted for 3.125%. The resistance rates of gram positive cocci to penicillin, cephalosporins, erythromycin and clindamycin were all more than 50%, and the rate of resistance to linezolid and vancomycin was O. The resistance rate of gram negative bacilli to the third generation cephalosporin was more than 50%, and the rate of resistance to earbapenems and quinolones was lower. The prevalence rate of fungal resistance is low. Conclusion：The resistance rate of eephalosporin antibiotics used in routine open heart surgery prevention is not excellent, so the prevention of postoperative wound infection should be considered in many aspects.

关 键 词：心脏直视手术 感染 病原菌 耐药性 

分 类 号：R446.5[医药卫生—诊断学]