赵炳南教授论治正虚邪盛皮肤病用药规律探析  

Cluster analysis of medicinals used by Prof. Zhao Bingnan in the treatment of skin disorders with the pattern of deficient healthy and excessive pathogenic qi

作　　者：杨旭杰[1,2] 裴晓华 王春晖 沈慧 

机构地区：[1]河北中医学院,河北050200 [2]北京中医药大学第三附属医院

出　　处：《北京中医药大学学报》2017年第12期1037-1043,共7页Journal of Beijing University of Traditional Chinese Medicine

基　　金：中国博士后基金资助项目(No.2016M600973);北京市哲学社会科学规划资助项目(No.17GLC062)~~

摘　　要：目的探求赵炳南教授论治正虚邪盛型皮肤病用药规律。方法收集赵炳南论治皮肤病的临床医案,筛选正虚邪盛型皮肤病处方353首,运用层次、迭代两种聚类分析方法挖掘复方药物特点,进而探讨其组方遣药规律。结果 353首复方涉及94种中药,聚为2类,第一类11种药物的用量、使用频次、君药比重占据明显优势。结论名医经验挖掘获得的高频中药总共11味,但是功效范围却涵盖了补气健脾、养血滋阴、升阳托毒、清热凉血、利水渗湿、排脓生肌、疏肝活血等诸多领域,足见其整体调治路线以及辨治的时序性、层次性及因果关系,名老中医经验挖掘对于充实皮肤领域学术内涵意义重大。Objective To explore the feature of medicinals used by Prof. Zhao Bingnan in treating skin disorders with the pattern of deficient healthy qi and excessive pathogenic qi. Methods Medical records of Prof. Zhao＇s patients with skin disorders were collected and 363 prescriptions were selected as the pattern diagnosis was deficient healthy qi and excessive pathogenic qi,whose rule of herbal combination would be probed by means of cluster analysis（ Hierachical Cluster and K-means Cluster）. Results 363 prescriptions involving 94 Chinese herbs were clustered into two categories. The first category,as the major category with much higher dosage,frequency,monarch position in the formula,included eleven kinds of Chinese herbs. Conclusion Eleven kinds of Chinese herbs were frequently used in treating skin disorders of deficient healthy qi and excessive pathogenic qi,with the major effects of nourishing blood or yin,clearing heat and cooling blood,eliminating turbidity and etc. This demonstrates a holistic,comprehensive,sequenced and stepwise approach to treatment. Analyzing and summarizing aged famed TCM practitioners＇ experiences in the choice of Chinese medicinals would contribute to the enrichment of TCM dermatology.

关 键 词：赵炳南 用药规律 皮肤病 正虚邪盛 聚类分析 

分 类 号：R275[医药卫生—中医皮科]