岭南传统天灸对膝痹患者的生存质量影响  

Effects of Lingnan traditional herbal patch on quality of life in patients with bi-syndrome of knee

作　　者：雷丽芳 徐书君 武仲遵 周俊合 徐振华 符文彬 

机构地区：[1]广州中医药大学第二附属医院,广东510120 [2]胡志明市医科大学 [3]广州中医药大学第二临床医学院

出　　处：《北京中医药大学学报》2017年第12期1050-1056,共7页Journal of Beijing University of Traditional Chinese Medicine

基　　金：国家“十一五”科技支撑计划资助项目(No.2006BAI12B04-1);广东省科技厅科技计划资助项目(No.2014A020212453);广东省中医院中医药科学技术研究专项资助项目(No.2014KT1547,No.2014KT1303)~~

摘　　要：目的评价岭南传统天灸疗法对膝痹患者的生存质量影响。方法共纳入93例患者,按简单随机法,随机分配到治疗组47例及安慰组46例。治疗组采用岭南传统天灸疗法治疗,安慰组采用安慰剂治疗,选穴均相同。疗效评价方面,运用患者报告结局(PRO)的方法,采用视觉模拟评定表(VAS)、膝关节功能主观评价表模拟评定表(IKDC)、健康调查筒表(SF-36)量表。结果 2组患者的VAS评分均下降,经方差分析,组间有显著性差异(F=10.912,P=0.003;F=28.351,P=0.020;F=7.072,P=0.016);对VAS减分率分析,治疗后的各评测时点,治疗组减分率分别为35.40%,62.03%,66.32%,安慰组的减分率分别为18.01%,18.35%,18.01%,组间有显著性差异(P=0.000)。IKDC评分方面,2组均呈下降趋势,组间有显著性差异(F=212.976,P=0.000;F=105.554,P=0.000;F=121.007,P=0.000)。SF-36量表方面,干预后,2组生理健康总评分(PCS)总评分均上升;而在随访1个月及随访3个月时点,2组PCS总评分测量示均下降,两两比较示,组间有显著性差异(P<0.05);在心理健康总评分(MCS)总评分方面,经干预后2组MCS总评分测量均上升,而随访3个月时点,两组MCS总评分均下降;两两比较示,组间有显著性差异(P<0.05)。提示两组的治疗均可对膝痹的疼痛、主观症状和客观体征、生理健康及心理健康方面均有改善作用,且以治疗组最优。结论岭南传统天灸对改善膝痹患者的生存质量有着积极的作用。Objective To evaluate the effects of Lingnan traditional herbal patch on quality of life among patients with knee bi-syndrome（ osteoarthritis）,in traditional Chinese medicine. Methods 93 patients were randomly assigned into treatment group（ 47 cases） and placebo group（ 46 cases）. The former group was treated with the Lingnan traditional herbal patch therapy while the lattfer group received placebo treatment with the same acupoints selected for both groups. Patient report outcome（ PRO） model was used for outcome measurement,using VAS,IKDC,and SF-36 scalesto evaluate the clinical effect at the following timepoints： before treatment,after treatment,1-month follow up,and 3-month follow up. Results VAS score of both groups were decreased. There were significant differences between the two groups at each time point（ F = 10. 912,P = 0. 003; F = 28. 351,P = 0. 020; F = 7. 072,P = 0. 016）.VASreduction rates after treatment in the treatment groups were 35. 40%,62. 03%. 66. 32%,and they were 18. 01%,18. 35%,18. 01% in the placebo group respectively. There were significant differences between the two groups（ P = 0. 000）. IKDC scores of the two groups were lower than before,and the difference between the two groups after treatment were statistically significant（ F = 212. 976,P = 0. 000,F = 105. 554,P = 0. 000,F = 121. 007,P = 0. 000）. The PCS scoresof both groups were increased after treatment; however,theyreduced at the 1-monthfollow-up and 3-monthfollow-up time pointcompared with the after-treatment time pointwith statistically significant difference（ P〈0. 05）; MCS scoresof both groups increased after treatment. Butscores of two groups were decreased at the 3-month follow-up time point with pairwise comparison; differences between treatment group and placebo groups were statistically significant（ P〈0. 05）. Herbal patch treatment can better relieve the pain,improve knee function and reduce symptoms of the knee osteoarthritic patients. Conclusion This study showed that Lingnan traditi

关 键 词：针灸 膝骨关节炎 膝痹 天灸 外治法 

分 类 号：R245.8[医药卫生—针灸推拿学]