难治性继发性甲状旁腺功能亢进的超声表现与实验室指标的相关性  

Correlation between ultrasound features of refractory secondary hyperparathyroidism and lab indexes

作　　者：李军[1] 王宏桥[2] 李秀梅[2] 宁春平[2] 姜彩云[2] 周茂平[2] 李强[2] 刘春晖[2] 

机构地区：[1]青岛大学,山东青岛266000 [2]青岛大学附属医院超声医学科,山东青岛266000

出　　处：《中国医学影像技术》2018年第1期39-42,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨难治性继发性甲状旁腺功能亢进(SHPT)的超声表现与实验室指标间的相关性。方法对30例难治性SHPT患者术前行二维超声及CEUS检查,测量并计算甲状旁腺体积和及增强区域体积和。记录术前2天内实验室检验指标水平,包括血清全段甲状旁腺激素(iPTH)、血清钙、血清磷、血清碱性磷酸酶(ALP)。计算校正血清钙、校正血清钙磷乘积。分析甲状旁腺体积和与各检验指标的相关性。结果甲状旁腺体积和、增强区域甲状旁腺体积和与iPTH呈正相关(r=0.48、0.50,P均=0.01),而与血清钙、血清磷、ALP、校正血清钙、钙磷乘积间无相关性(P均>0.05)。结论超声测算的甲状旁腺体积和可反映甲状旁腺活性状态,为诊断及监测SHPT提供参考。Objective To analyze correlation between ultrasound features and clinical lab indexes of refractory secondary hyperparathyroidism （SHPT）. Methods Two-dimensional ultrasound and CEUS were performed in 30 patients with refractory SHPT before operation. The sum volume of hyperplastic parathyroid glands and sum volume of enhanced area of parathyroid glands in each patient were measured and calculated. Clinical lab indexes, including serum intact parathyroid hormone （iPTH）, serum calcium, serum phosphorus, serum alkaline phosphatase （ALP） were recorded, and corrected serum calcium and corrected serum calcium-phosphorus product were calculated 2 days before operation. The correlation between sum volume of parathyroid glands and lab indexes was analyzed. Results There were positive correlations （r= 0.48, 0.50, both P= 0.01） between sum volume of parathyroid glands, sum volume of enhanced area of parathyroid glands and iPTH level. No correlation was found between the volume of hyperplastic parathyroid glands and serum calcium, serum phosphorus, ALP, corrected serum calcium, nor calcium-phosphorus product （all P〉0.05）. Conclusion The sum volume of parathyroid can reflect active state of parathyroid glands, which is helpful to diagnosis and monitoring refractory SHPT.

关 键 词：甲状旁腺功能亢进 超声检查 甲状旁腺激素 

分 类 号：R445.1[医药卫生—影像医学与核医学] R582.1[医药卫生—诊断学]