附子减毒方式与药效浅析  

Attenuated Way and the Efficacy of Fuzi(Aconite)

作　　者：强小娟 朱智慧 姜黎[1] 蔡涛[1] 

机构地区：[1]彭州市中医医院,四川彭州611930

出　　处：《中医药导报》2018年第1期34-36,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：<全国中药特色技术传承人才>培训项目资助

摘　　要：目的:浅析附子减毒方式与药效的关系。方法:通过查阅资料,分析附子的炮制、配伍、煎煮、限量减毒方式与药效的关系。结果:发现附子炮制减毒方式不同,药效有异,但存在炮制过度现象;合理配伍可减毒增效;久煎能降低附子的毒性,但有实验表明合煎比先煎附子获得的减毒效果更显著;降低剂量可以保证附子的使用安全,但量效之间需要平衡。结论:附子减毒的目的是保证其在临床应用上的安全性,但应注意存效和增效。Objective： To analyze the relationship of Fuzi （Aconite）, between the way decrease toxicity and efficacy. Methods： By the literatures, we accounted these factors including processing, compatibility, lateral root of aconite decoction, limited attenuated way, and then found the relationship with the efficacy. Results： Clinical curative effect may be inflected for monkshood attenuated in different ways, but there is processing excessive phenomenon; Reasonable compatibility can be attenuated synergies; Long decoction can reduce the toxicity of lateral root of aconite, but there are experiments showed that frying than first decoct of lateral root of aconite attenuated the effect is more significant; Lower doses can ensure the safety of the use of lateral root of aconite, but need to balance between volume effect. Conclusion： The monkshood attenuated purpose is to guarantee its safety in clinical application, but we should pay attention to the effect and efficiency.

关 键 词：附子 炮制减毒 配伍减毒 煎煮减毒 限量减毒 药效 

分 类 号：R283[医药卫生—中药学]