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作 者:闫慈[1] 田翔华[2] 阿拉依.阿汗 张伟文[1] 曹明芹[1]
机构地区:[1]新疆医科大学公共卫生学院,新疆乌鲁木齐830011 [2]新疆医科大学工程技术学院,新疆乌鲁木齐830011
出 处:《现代预防医学》2018年第1期160-163,共4页Modern Preventive Medicine
基 金:新疆科技之疆项目(2016E02082);国家自然科学基金(71663053)
摘 要:目的分析乌鲁木齐市体检人群代谢综合征的患病特点,探讨代谢综合征病理生理机制。方法选择乌鲁木齐市某体检中心代谢综合征患者数据,描述性分析不同年龄、不同性别的代谢综合征患者各组分患病情况及聚集情况。采用因子分析方法,探讨不同性别代谢综合征9项指标组分:体质指数、空腹血糖、收缩压、舒张压、高密度脂蛋白、低密度脂蛋白、腰围、甘油三酯、总胆固醇的潜在支配因子。结果 (1)代谢综合征各组分患病率由高到低依次为超重或肥胖、高血压、高血糖、高血脂。(2)最常见的代谢综合征组合形式为肥胖+高血压+高血糖。(3)不同性别因子分析显示,肥胖因子、血压因子、脂代谢因子、糖耐量因子是代谢综合征的潜在支配因子。共性因子的累积贡献率在男性和女性中分别为71.47%和67.38%。男性中主导因子为肥胖因子,女性为血压因子。结论乌鲁木齐市代谢综合征病理生理机制复杂,预防代谢综合征的发生应从以上4个因子出发。尤其是男性注意控制体重,女性注意控制血压。Objective To analyze the prevalence of metabolic syndrome with physical examination population in Urumqi, and to explore the pathophysiological mechanism of metabolic syndrome. Methods We selected the data of physical examination center with metabolic syndrome in Urumqi. We adopted descriptive analysis constitution and aggregation of metabolic syndrome components in different gender and age. Factor analysis was used to reveal underlying factors among metabolic variables of metabolic syndrome,which included body mass index,fasting plasma glucose, systolic blood pressure, diastolic blood pressure, high - density lipoprotein cholesterol, low - density lipoprotein cholesterol, waist circumference, triglyceride and total cholesterol. Results ( 1 ) The prevalence rate from high to low of metabolic syndrome components were overweight or obesity, hypertension, hyperglycemia and hyperlipidemia. (2) The most common form of metabolic syndrome was obesity + hypertension + hyperglycemia. ( 3 ) Factor analyses of different sex showed that obesity factor, blood pressure factor, lipid metabolism factor and glucose tolerance factor were the potential dominant factors for metabolic syndrome. The cumulative contribution rate of the common factors were 71.47% and 67.38% for male and female, respectively. The leading factors were obesity factor and blood pressure factor for male and female, respectively. Conclusion The pathogenesis of metabolic syndrome in Urumqi is complicated. The prevention of metabolic syndrome should be based on the above 4 factors. In particular, people should pay attention to control weight and blood pressure for male and female respectively.
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