SrO改性SiO_2-B_2O_3-CaO-P_2O_5系生物玻璃的制备及体外生物活性研究  

Preparation and in vitro bioactive properties of SrO modified SiO_2-B_2O_3-CaO-P_2O_5 system bioactive glasses

作　　者：殷海荣[1] 杨晨[1] 郭宏伟[1] 童强 高杨 李明阳 

机构地区：[1]陕西科技大学材料科学与工程学院,陕西西安710021

出　　处：《陕西科技大学学报》2018年第1期102-105,111,共5页Journal of Shaanxi University of Science & Technology

基　　金：国家科技部重点研发计划专项项目(2017YFGX010110);国家自然科学基金项目(51472151);咸阳市科学技术研究计划项目(2016K02-28)

摘　　要：以SiO_2-B2O_3-CaO-P_2O_5系生物玻璃配方为基础,添加0~9mol%的SrO,采用聚合物泡沫模板法制备了生物玻璃支架材料.通过差示扫描量热法(DSC)、扫描电子显微镜(SEM)、傅里叶红外光谱(FTIR)、X射线衍射(XRD)、电感耦合等离子发射光谱(ICP)等技术研究了SrO添加量对生物玻璃结构和体外生物活性的影响.结果表明,该体系生物玻璃烧结温度为530℃,气孔率为85%,抗压强度为12MPa.随着SrO含量增加,玻璃结构中Si-O键在逐渐减弱.在模拟体液(SBF)中同一时间里,Ca离子浓度随着SrO含量增加而增加,B离子浓度随着SrO含量增加在逐渐减小,该体系生物玻璃具有良好的生物活性.SiO_2-B_2O_3-CaO-P_2O_5 system bioactive glasses added with 0~9 mol% SrO were prepared by apolymer foam replication method.The effect of SrO content on the structure and bioactive properties were investigated with DSC,SEM,FTIR,XRD,ICP method.The results showed that the sintering temperature of the bioactive glasses is 530 ℃,the porosity is85% and the compressive strength is 12 MPa.With the increasement of SrO in glass structure,the intensity of Si-O vibrations decreased.The concentration of Ca2+increased and the concentration of B3+decreased with the increasement of SrO after immersing in SBF for the same time,and the bioglass exhibited good bioactivity.

关 键 词：生物玻璃 锶 硼离子浓度 生物活性 

分 类 号：TQ171.1[化学工程—玻璃工业]