St.Gallen会议乳腺癌新辅助治疗回顾  

Review of neoadjuvant therapy for breast cancer at the St.Gallen conference

作　　者：石爱平[1] 徐格格 解新鹏 

机构地区：[1]吉林大学第一医院乳腺外科,吉林长春130021

出　　处：《山东大学学报（医学版）》2018年第1期6-11,21,共7页Journal of Shandong University:Health Sciences

基　　金：国家自然科学基金(30300336);白求恩计划B(2012217)

摘　　要：新辅助治疗作为局部晚期乳腺癌的治疗方式,可使不可手术的乳腺癌转为可手术,为不可保乳的患者,最终保留了乳房。现今,一些新的证据又赋予了新辅助治疗新的使命,包括筛选敏感药物,使患者病情达到病理完全缓解,从而生存获益;另外,使腋窝病理缓解的患者避免腋窝清扫。本文综述了St.Neoadjuvant therapy is the standard treatment for local advanced breast cancer. Some inoperable breast cancer can be operated and some patients who should not undergo breast conservative surgery can keep their breast after neoadjuvant therapy. Nowadays, based on new evidences, there are new missons in neoadjuvant therapy, such as screening out sensitive drugs for the patients who may acquire pathological complete reaction in order to gain survival benefits and avoiding axillary dissection for some patients who are clinically nodes positive at diagnosis and downstage. The new progress of neoadjuvant therapy at St. Gallen conference will be reviewed in the paper.

关 键 词：乳腺癌 新辅助治疗 病理完全缓解 保乳手术 腋窝清扫 化疗 内分泌 

分 类 号：R605[医药卫生—外科学]