口服益生菌对极低出生体重儿早期生长发育影响的临床研究  

Clinical study on effects of oral probiotics on early growth and development among very low birth weight infants

作　　者：李燕 李雪梅[1] 吴全兰[1] 周晓军[1] 

机构地区：[1]重庆市妇幼保健院,400014

出　　处：《中国妇幼卫生杂志》2017年第6期33-35,共3页Chinese Journal of Women and Children Health

基　　金：基金项目:中国疾病预防控制中心妇幼保健中心(2015FYH003)

摘　　要：目的探讨益生菌对极低出生体重儿早期生长发育的影响。方法收集2015年5月-2017年5月重庆市妇幼保健院新生儿科住院治疗的极低出生体重儿61例,采用随机双盲法分为实验组和对照组,实验组30例,对照组31例。两组患儿均予以常规护理及治疗,实验组在此基础上补充益生菌(从肠内喂养前开始补充直至出院),收集两组患儿一般资料,以及出院体重、出院头围、出院身长、住院天数、恢复出生体重天数,根据结果计算头围、身长及体质量增长速率。结果两组患儿的头围和身长增长速率比较差异无统计学意义,而实验组体质量增长速率高于对照组(P<0.05)。结论口服益生菌能加快极低出生体重儿的体质量增长速率。Objective To explore the effects of probiotics on early growth and development of very low birth weight infants. Methods From May 2015 to May 2017, a total of 61 very low birth weight infants who hospitalized in neonatal department of Chongqing Women and Children＇ s Health Care Hospital were selected as the subjects. The random double blind method was used to divide the subjects into two groups, including the experimental group and the control group. There were 30 cases and 31 cases in the experimental group and the control group, respectively. Both of the two groups received usual care and treatment. At the same time, the experimental group was also supplemented with probiotics （from enteral feeding until discharge）. The general data, parameters of head circumference, length and body weight on the discharge day, inpatient days and restoration days of birth weight were collected. The growth velocity of head circumference, length, body weight was calculated according to the result. Results There was no statistically significant difference in head circumference and length growth rate between the two groups. The weight growth velocity of the experimental group was higher than that of the control group. Conclusion Oral probiotics may improve the growth velocity of weight among the low birth weight infants.

关 键 词：益生菌 极低出生体重儿 体质量增长速率 

分 类 号：R722.6[医药卫生—儿科]