侧弯动物模型的脊柱韧带结构及研究进展  

The Research of Spinal Ligament in Scoliosis Animal Model

作　　者：贾楠[1] 李鹏飞[1] 沈亚欣 靳宪辉[1] 

机构地区：[1]哈励逊国际和平医院外科,衡水053000 [2]河北医科大学外科学教研室,石家庄050000

出　　处：《实验动物科学》2017年第6期65-69,74,共6页Laboratory Animal Science

摘　　要：建立动物模型是研究脊柱侧弯的重要方法。解剖二足动物、伪二足动物、四足动物模型的脊柱韧带,并研究这些韧带的神经支配,使脊柱侧弯动物模型的建立方法逐渐得到了拓展。脊柱中央韧带在所有动物中都可发现,而侧方韧带只存在于二足(灵长类)及伪二足(鸟类)物种,脊柱侧方韧带并未在四足动物中发现。在对二足及伪二足动物研究中发现,侧方韧带结构明显维持了脊柱的稳定性,是保持脊柱直立性的基础,反应了动物直立行走后脊柱生理学应力的增加。脊柱韧带生物力学失衡必然会引起并加剧脊柱畸形,产生恶性循环。作者在此对脊柱韧带的发现、应用及研究进展做出综述。The establishment of animal models is an i legged animals, pseudo two legged animals and te ligaments was studied. The method of establishing ligament of the spine can be found in all animals, pseudo two legged （bird） species, and the lateral mportant method to study scoliosis. The spinal ligaments of two trapod models were dissected, and the innervation of these oliosis animal models was gradually expanded. And the central while the lateral ligament only exists in two feet （primates） and ligament of the spine is not found in tetrapods. In the study of two feet and two legged animals, it was found that the lateral ligament structure significantly maintained the stability of the spine. And the lateral ligament structure was the basis for maintaining the upright of spine, which reflected the increase of the physiological stress of the spine after the animals walked upright. Spinal ligament biomechanics imbalance will inevitably cause and exacerbate spinal deformities, resulting in a vicious circle. In this review, the discovery, application and research progress of spinal ligament are reviewed.

关 键 词：侧弯 动物模型 脊柱 韧带 

分 类 号：R3[医药卫生—基础医学]