神经节苷脂联合依达拉奉治疗一氧化碳中毒后迟发性脑病的临床观察  

Clinical observation of ganglioside combined with edaravone in the treatment of delayed encephalopathy after carbon monoxide poisoning

作　　者：郭建强 郑婷婷 张蓉[1] 波顺庆[1] 严治[1] 汤兴华[1] 

机构地区：[1]三峡大学第一临床医学院,宜昌市中心人民医院,443003

出　　处：《中国社区医师》2018年第2期32-32,34,共2页Chinese Community Doctors

摘　　要：目的:探讨神经节苷脂联合依达拉奉治疗一氧化碳中毒后迟发性脑病的临床疗效。方法:收治中重度一氧化碳中毒后迟发性脑病患者86例,随机分为观察组和对照组。对照组采用高流量吸氧、减轻颅脑水肿与脑细胞营养药物及高压氧等基础支持疗法,观察组在对照组基础上加用神经节苷脂与依达拉奉,比较两组治疗效果。结果:观察组总有效率明显高于对照组(P<0.05)。结论:神经节苷脂联合依达拉奉治疗中重度一氧化碳中毒后迟发性脑病效果显著。Objective：To explore the clinical effect of ganglioside combined with edaravone in the treatment of delayed encephalopathy after carbon monoxide poisoning.Methods：86 patients with moderate and severe delayed encephalopathy after carbon monoxide poisoning were selected.They were randomly divided into the observation group and the control group.The control group was treated with high flow oxygen,reducing brain edema and brain cell nutrition drugs and hyperbaric oxygen and other basic supportive therapy.The observation group was treated with ganglioside combined with edaravone on the basis of the control group.We compared the treatment effect of two groups.Results：The total effective rate of the observation group was significantly higher than that of the control group（P〈0.05）.Conclusion：The clinical effect of ganglioside combined with edaravone in the treatment of delayed encephalopathy after carbon monoxide poisoning was significant.

关 键 词：一氧化碳中毒迟发脑病 高压氧 神经节苷脂 依达拉奉 

分 类 号：R595.1[医药卫生—内科学] R742[医药卫生—临床医学]