五神针治疗轻中度痰浊阻窍型血管性痴呆的临床观察  

Acupuncture at Baihui and Sishencong in Treatment of Vascular Dementia of Phlegm Obstructing Intelligence Type

作　　者：王飞[1] 王民集[2] 

机构地区：[1]河南中医药大学针推学院,河南郑州450008 [2]河南中医药大学第三附属医院针灸科,河南郑州450003

出　　处：《辽宁中医杂志》2017年第12期2617-2619,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：河南省中医药大学博士科研基金项目(BSJJ2014-21)

摘　　要：目的:探讨五神针治疗轻中度痰浊阻窍型血管性痴呆(VD)的临床疗效及安全性。方法:将120例轻中度痰浊阻窍型VD患者按随机数字表法分为基础治疗组、传统针刺组和五神针组,每组40例。基础治疗组给予常规的基础治疗,传统针刺组在基础治疗组治疗基础上取传统针刺穴位进行治疗,五神针组在基础治疗组治疗基础上针刺百会,四神聪为主穴进行治疗,疗程均为36 d。比较各组治疗前后简易精神状态量表(MMSE)、日常生活能力量表(ADL)、痴呆简易筛查量表(BSSD)和VD中医辨证量表痰浊阻窍型分表(中医证候)的评分;检测治疗前后超氧化物歧化酶(SOD)、过氧化脂质(LPO)和丙二醛(MDA)的变化。结果:治疗后五神针组总有效率89.5%,显著高于基础治疗组74.4%(P<0.01)和传统针刺组的81.1%(P<0.05);五神针组MMSE、ADL、BSSD和中医证候评分较基础治疗组和传统针刺组改善更为显著(均P<0.05或P<0.01);五神针组SOD、LPO和MDA水平的改善优于基础治疗组和传统针刺组(均P<0.05)。结论:五神针组可显著提高痰浊阻窍型血管性痴呆患者的MMSE、ADL、BSSD评分,改善SOD、LPO和MDA的水平,其临床疗效优于基础治疗组和传统针刺组。Objective ： To explore the therapeutic effect in treatment of vascular dementia of phlegm obstructing intelligence type with acupuncture at Baihui and Sishencong. Methods：A total 120 cases of vascular dementia of phlegm obstructing intelligence type were randomlydivided into the acupuncture at Baihui and Sishencong group, acupuncture at traditional points group and basic treatment group,40 cases in each one. The acupuncture at Baihui and Sishencong group wasapplied the acupuncture at Baihui and Sishencong. The acupuncture at traditional points group used the acupuncture at Fengchi, Gongxue, Hegu, Benshen, Taixi, Dazui, Mingmen and Xuehai and the basis treatment was adopted the basic treatment. A course was 28 d. Hastgawa Dementia Scale （HDS） and the mini - mental state examination （ MMSE）, the activities of daily living （ ADL）, the brief screening scale for demen- tia （BSSD）and the scale for the differentiation of syndromes of vascular dementia（ TCM symptom）were applyied to estimate the ef- ficacy of the 3 groups beforeand after treatment. The superoxide dismutase （ SOD）, lipid peroxidation （LPO） and serum levels of malondialdehyde（MDA） were detected. Results：The efficiency of acupuncture at Baihui and Sishencong group was 89.5%, better than acupuncture at traditional group＇s 81.1% and the basic treatment group＇s 74.4% （ all P 〈 0. O1 ）. After treatment, the scores of MMSE, ADL, BSSD and TCM symptom have improved significantly （ all P 〈 0. 05 ） in the three groups. The acupuncture at Baihui and Sisheneong group was superior to the others. The detection of SOD, LPO and MDA in the acupuncture at Baihui and Sishencong group was better than the other two groups （ all P 〈0. 05 ）. Conclusion ： To treat vascular dementia of phlegm obstruc- ting intelligence type with acupuncture at Baihui and Sishencong is remarkable.

关 键 词：五神针 痰浊阻窍型 血管性痴呆 临床观察 

分 类 号：R246.1[医药卫生—针灸推拿学]