民族药过江藤的化学成分及药理作用研究进展  

Research Advance on Phytochemistry and Pharmacological Actions for Ethnomedicine Phyla nodiflora( Verbenaceae)

作　　者：杨勇勋[1] 马金华 

机构地区：[1]西昌学院动物科学学院,四川西昌615000

出　　处：《中国民族民间医药》2018年第1期69-74,共6页Chinese Journal of Ethnomedicine and Ethnopharmacy

基　　金：四川省教育万理工科重点项目(14ZA0213);西昌学院博士启动项目(15BZ02)

摘　　要：马鞭草科过江藤属在我国仅有1种,即植物过江藤Phyla nodiflora。在文献中,Lippia nodiflora也指过江藤Phyla nodiflora植物,两名互用。过江藤Phyla nodiflora不仅在我国多个民族中作为民族药应用,且在多个国家作为传统药物应用于多种疾病的治疗。从过江藤植物中分离的化合物达30余个,涉及的化学成分类型主要是环已烯酮与环已二烯酮衍生物、酚酸、三萜、甾醇、黄酮及黄酮硫酸盐等。另外,药理研究揭示本品的活性谱较宽,且大多与其传统应用相关,如利尿、抗尿路结石、抗高尿酸血症、肝保护、神经药理作用等。综述过江藤的化学及药理研究进展,为其进一步开发与利用打好基础。Phyla nodiflora belonging to the family Verbenaceae is the solo species in the genus Phyla in China. Lippia is properly called Phyla, but is referred to as Lippia in the phytochemical literature, i. e. the synonym of Phyla nodiflora is Lippia nodiflora. Phy- la nodiflora is not only used as an ethnomedicine in China, but also utilized as a traditional medicine in the world, for the treatment of several diseases. So far, more than 30 compounds including cyclohexenoue and cyclohexadienone derivatives, phenolic acids, triterpe- nes, sterols, fiavonoids, and flavone sulphates were isolated from Phyla nodiflora. Moreover, the modem pharmacological studies of its crude extracts and purified molecules showed that its pharmacological spectra are broad, and quite a few activities were correlated with its traditional uses, such as diuretic activity, urolithiasis, hepatoprotective activity, and neuropharmacological activity. This review comprehensively summarized the pharmacological effects of Phyla nodiflora and its chemical constituents, establishing a solid founda- tion for the further development and utilization of the title plant.

关 键 词：马鞭草科 过江藤 化学成分 药理作用 

分 类 号：R285[医药卫生—中药学]