2016年辽宁省人间布鲁氏菌病治疗结果分析  

Analysis of the treatment surveillance data in the human brucellosis in Liaoning in 2016

作　　者：王子江[1] 于维君[1] 毛玲玲[1] 孙英伟[1] 姚文清[1] 

机构地区：[1]辽宁省疾病预防控制中心,沈阳110005

出　　处：《医学动物防制》2018年第1期18-21,共4页Journal of Medical Pest Control

基　　金：国家科技重大专项课题-艾滋病和病毒性肝炎等重大传染病防治项目辽宁及周边省(市)传染病病原谱流行规律研究(2012ZX10004-209);国家科技重大专项课题-肝炎;结核等重大疾病临床研究平台建设(2013225079)

摘　　要：目的了解辽宁省当前布鲁氏菌病(简称布病)治疗情况,并探索与布病抗生素治疗转归相关的影响因素,针对影响因素采取措施,提高病人治愈率。方法收集辽宁省2016年人间布病主动监测方案中选择抗生素治疗的人群为研究对象,记录一般人口学信息、流行病学信息、临床诊断及随访转归结果。结果共完成1 389例病例信息收集及随访,治愈率为51.5%,发热症状与布病抗生素治疗转归效果间存在统计学关联(OR=1.881)。另外,临床分期中急性期布病与转归效果间存在统计学关联,是影响转归的危险因素(OR=1.904,95%CI:1.014~3.578)。结论辽宁省人间布病主动监测是布病作为传染性疾病监测的重要补充,总体治愈效果较好,加强对急性期病例的督导治疗有利于提高短期内治疗转归效果。Objective To get acknowledgement of the treatment situation of human brucellosis and to explore influence factors related to antibiotic therapy,aiming at improving the cure rate of human brucellosis. Methods People chose antibiotic treatment was collected from human brucellosis active surveillance data in Liaoning in 2016. General demographic information,epidemiological information,clinical diagnosis and follow-up outcome results were recorded. Results A total number of 1 389 cases was collected and followed up,and the cure rate was 51. 5%. After statistics,there was a statistical correlation between the fever symptom and the outcome of the disease,and the OR was 1. 881. In addition,there was a statistical correlation between the acute period in the clinical score and the outcome of the disease,which was the risk factor related to the revery of the disease with1. 904（ 95% CI： 1. 014 ~ 3. 578） of the OR. Conclusion The active surveillance of human brucellosis in Liaoning was an important complement to the infectious disease surveillace. The overall treatment is better. It was important to improve the treatment by enhancing treatment surveillace of the patients in acute stage of brucellosis.

关 键 词：布鲁氏菌病 抗生素治疗 主动监测 

分 类 号：R516.7[医药卫生—内科学]