泛素/26S蛋白酶体途径在水稻中的生物学功能研究进展  

Biological Function Insights into the Ubiquitin/26S Proteasome Pathway in Rice

作　　者：徐丹丹 孙帆 王银晓 石英尧[1] 王文生[2] 傅彬英[2] 

机构地区：[1]安徽农业大学农学院,合肥230036 [2]中国农业科学院作物科学研究所农作物基因资源与基因改良国家重大科学工程,北京100081

出　　处：《中国农业科技导报》2018年第1期25-33,共9页Journal of Agricultural Science and Technology

基　　金：国家自然科学基金项目(31501291;U13022168);"十二五"国家科技支撑计划项目(2015BAD01B02-3)资助

摘　　要：生物体内的蛋白质降解方式有两种,一种不需要能量,一种需要能量。而泛素/26S蛋白酶体途径便是目前已知的依赖ATP、高效、有高度选择性的蛋白降解途径。它介导了真核生物中80%~85%的蛋白质降解,几乎参与到植物生长发育的各个环节,是植物体内蛋白高效专一降解最重要、最精细的调控机制之一。概述了泛素蛋白酶体途径,重点阐述了泛素结合酶E2和泛素连接酶E3的蛋白结构及其在水稻生长发育、激素信号传导、生物和非生物胁迫响应中的生物学功能及机制,并对进一步研究进行了展望,将有助于揭示泛素/26S蛋白酶体途径在水稻生长发育中的精细调控过程,并为水稻抗逆育种提供了指导和借鉴。There are two different protein degradation patterns in vivo, one pattern is energy-dependent and another is energy-independent. Ubiquitin/26S proteasome pathway （UPP） is an exceedingly high-efficient, specific and ATP- dependent route for protein removal. In eukaryote, ubiquitin/26S proteasome pathway is involved in 80% ~ 85% protein degradation. In plant species, the ubiquitin/26S proteasome pathway regulates fundamental processes of growth and development, and it is one of the most important and fine regulation mechanisms for protein efficient and specific degradation in plants. This paper summarized the ubiquitin/26S proteasome pathway, and emphasized on the protein structure of E2 and E3 and their biological function and mechanism in rice growth and development, hormone signaling, biotic and abiotie stress response. The paper also prospected the further study, which would be helpful for revealing the fine control process of ubiquitin/26S proteasome pathway during rice growth and development, thus to provide guidance and reference for rice stress resistance breeding.

关 键 词：泛素蛋白酶体途径 水稻 泛素结合酶E2 泛素连接酶E3 生物学功能 

分 类 号：S511[农业科学—作物学]