益生菌抗氧化机制的研究进展  

Advances in Antioxidant Mechanisms of Probiotics

作　　者：贺驭 孔祥峰[2] 王振勇[3] 黄帆[1] 王一涵 吕秋凤[1] 

机构地区：[1]沈阳农业大学,辽宁沈阳110866 [2]中国科学院亚热带农业生态研究所,湖南长沙410125 [3]辽宁禾丰牧业股份有限公司,辽宁沈阳110164

出　　处：《中国家禽》2017年第24期41-44,共4页China Poultry

基　　金：国家重点研发计划项目(2017YFD0500500)

摘　　要：氧化应激是细胞中氧化物与抗氧物的平衡受到干扰,导致DNA羟基化,蛋白质变性,脂质过氧化和细胞凋亡,最终影响细胞活力。益生菌能够影响肠道菌群变化,调节肠道Ph,促进有益菌增殖。研究发现益生菌也具有抗氧化活性并减少由氧化引起的损伤的能力。本文从益生菌的改善抗氧化系统的能力和减少自由基产生的能力以及益生菌介导的抗氧化信号通路等方面,结合近年来益生菌的抗氧化机制的研究做一综述。Oxidative stress is a disturbing balance of oxides and antioxidants in cells, leading to DNA hydroxylation, protein denaturation, lipid peroxidation and apoptosis, uhimatel~ affecting cell viability. Probiotics can affect intestinal flora, regulate intestinal Ph, and promote the proliferation of beneficial bacteria. Studies have also found that probiotics also have antioxidant activity and reduce the damage caused by oxidation. In this paper, probiotics probiotics in improving the ability of anti-oxidation system and reduce the ability of free radicals and probiotics-mediated anti-oxidative signaling pathway, combined with probiotics in recent years to study the mechanism of anti-oxidation are reviewed.

关 键 词：氧化应激 抗氧化剂 益生菌 信号通路 

分 类 号：Q936[生物学—微生物学]