ZnAl-BrO_3^--LDHs/KBr溴源在苯胺类化合物选择性氧化溴代的应用（英文）  

Selective Oxidative Bromination of Anilines Using Potassium Bromide and ZnAl-BrO_3^--LDHs

作　　者：王力耕[1] 陈璐焌 章华隆 余琴 

机构地区：[1]浙江工业大学化学工程学院,杭州310014

出　　处：《有机化学》2017年第12期3186-3190,共5页Chinese Journal of Organic Chemistry

摘　　要：以醋酸/水为溶剂,用溴酸根插层的水滑石和溴化钾为溴源,室温下完成对苯胺类化合物的选择性氧化溴代反应.成功合成苯胺类化合物的单溴代和多溴代的目标产物,并获得较高产率.考察了底物结构及反应条件对反应选择性的影响.应用该溴源试剂,环境友好,操作简单,产率高,是一种合成溴代苯胺类化合物的新途径.The oxidative bromination of anilines was realized with ZnAl-BrO_3^--LDHs/KBr as the bromine source at ambient temperature in acidic medium（AcOH/H_2O）. High yields of monobrominated or polybrominated anilines were achieved for a wide range of anilines. Both the substrate structure and the reaction conditions will significantly influence the reaction selectivity. The use of inexpensive reagents, environmentally benign and operationally simple process, and excellent yields make it a good alternative to the synthesis of bromoanilines.

关 键 词：苯胺类 卤化 选择性 芳香取代 

分 类 号：O625.633[理学—有机化学]