碘催化喹啉氮氧化物与磺酰肼的区域选择性磺酰化反应（英文）  

Iodine-Catalyzed Regioselective Sulfonylation of Quinoline N-Oxides with Sulfonyl Hydrazides

作　　者：余海洋 皮超 王勇[1] 崔秀灵[1] 吴养洁[1] 

机构地区：[1]郑州大学化学与分子工程学院河南省化学生物与有机化学重点实验室河南省高等学校应用化学重点开放实验室,郑州450052

出　　处：《有机化学》2018年第1期124-130,共7页Chinese Journal of Organic Chemistry

基　　金：supported by the Ministry of Science and Technology of China(No.2016YFE0132600);the Science and Technology Innovation Program of Universities in Henan Province(No.16HASTIT007)~~

摘　　要：发展了一种新型且简单的喹啉氮氧化合物的2位区域选择性磺酰化反应,此方法具有操作简单、高效能、环境友好、无金属添加等优势,脂肪和芳香磺酰肼都能以较好的收率得到2位磺酰化喹啉化合物.A novel and simple protocol has been developed for the regioselective sulfonylation of quinolone N-oxides at their C-2 postition. This method features with a simple system, high efficiency, environmental friendliness, and metal-free conditions. Aliphatic and aryl sulfonyl hydrazides smoothly undergo sulfonylation with quinoline N-oxides in good yields.

关 键 词：碘催化 喹啉氮氧 磺酰肼 

分 类 号：O621.251[理学—有机化学]