冰连清咽喷雾剂治疗急性咽炎及慢性咽炎急性发作多中心随机对照研究  

A multicenter randomized controlled study on the treatment of acute and chronic pharyngitis with Binglianqingye Spray

作　　者：陈建军[1] 殷善开[2] 刘世喜[3] 周慧芳[4] 郑宏良[5] 孔维佳[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院耳鼻咽喉科,武汉430022 [2]上海交通大学附属第六人民医院耳鼻咽喉头颈外科 [3]四川大学华西医院耳鼻咽喉头颈外科 [4]天津医科大学总医院耳鼻咽喉科 [5]第二军医大学附属长海医院耳鼻咽喉头颈外科

出　　处：《临床耳鼻咽喉头颈外科杂志》2018年第1期1-6,共6页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:评价冰连清咽喷雾剂对急性咽炎及慢性咽炎急性发作患者的临床疗效及其作用特点,并对其安全性进行评价。方法:通过分别以金嗓子喉片和金喉健喷雾剂为平行对照的随机、盲法、多中心临床试验,观察冰连清咽喷雾剂治疗急性咽炎及慢性咽炎急性发作患者360例。结果:冰连清咽喷雾剂能明显改善急性咽炎或慢性咽炎急性发作患者的咽痛、咽黏膜及悬雍垂红肿、咽干灼热、头痛、咳嗽症状,以及咽后壁淋巴滤泡充血肿胀及下颌角淋巴结肿痛等情况,临床疗效确切。同时受试者对冰连清咽喷雾剂口感满意度为82.1%。结论:冰连清咽喷雾剂治疗急性咽炎或慢性咽炎急性发作症状综合疗效良好且不良反应小,患者依从性高。Objective：To further evaluate the clinical efficacy and safety of Binglianqingye Spray on acute and chronic pharyngitis by clinical observation.Method：A randomized,double-blind and multicenter clinical trial which served Jinsangzi Tablet and Jinhoujian Spray as the control groups was conducted to observe the effect of Binglianqingye Spray on 360 patients with acute and chronic pharyngitis.Result：Binglianqingye Spray could significantly improve the symptoms with the exact clinical efficacy of the acute pharyngitis or chronic pharyngitis,such as sore throat,pharyngeal mucosa and uvula,dry throat burning,headache,cough,pharynx posterior wall lymphoid follicles hyperemia swelling and mandibular angle lymph node swelling and so on,but it occasionally occurred urine abnormalities and urine sugar adverse reactions.At the same time,the taste satisfaction was 82.1%.Conclusion：The combined effects of Binglianqingye Spray on the treatment of acute pharyngitis or chronic pharyngitis are well,the adverse reaction is rare and the patient′s compliance is high.

关 键 词：冰连清咽喷雾剂 急性咽炎 慢性咽炎急性发作 

分 类 号：R766.14[医药卫生—耳鼻咽喉科]