动物气溶胶暴露装置的特点及其应用  

The applications and characters of aerosol exposure device for animal

作　　者：郝新彦 张元慧[1] 高虹[1] 

机构地区：[1]中国医学科学院医学实验动物研究所北京协和医学院比较医学中心,北京100021

出　　处：《中国医学装备》2018年第1期127-130,共4页China Medical Equipment

基　　金：国家科技重大专项(2017ZX10304401-011)"高等级动物生物安全实验室污染活动的风险识别和控制的研究"

摘　　要：气溶胶暴露装置是进行呼吸道传染病研究、化学物质毒性鉴定、疫苗评价及药物研究的重要设备,被广泛用于呼吸系统疾病、毒理学、吸入免疫、安全性评价等领域,是进行实验动物气溶胶感染实验和吸入毒理学研究必不可少的技术平台。随着科技的发展和现实的需要,气溶胶暴露装置正朝着更加安全、高效、精确及自动化方向发展,并具有广泛的应用前景。通过综述动物气溶胶暴露装置的特点及应用,为气溶胶暴露装置的研究与应用选择提供科学依据。Aerosol inhalation exposure device provides important means for the studies of respiratory infectious disease, toxicity identification of chemical substance, vaccine evaluation and drug research, and now it is widely used in many fields included of respiratory diseases research, toxicology, inhalation immunity and safety evaluation. It is essential platform to do aerosol infection experiment of using laboratory animal and toxicology studies about inhalation. With the developments of science and technology and for the demand of reality, the device of aerosol exposure is developing in a more safe, efficient, precise and automatic direction, and it has a wide application prospect. Through reviews the characters and applications of inhalation exposure device, this paper will service as the scientific basis and references for further research and selection on the inhalation exposure device in future.

关 键 词：气溶胶暴露装置 实验动物 气溶胶感染 吸入毒理学 

分 类 号：R197.39[医药卫生—卫生事业管理]