严重烧伤患者锌缺乏与补锌治疗研究进展  

Advances in the research of zinc deficiency and zinc supplementation treatment in patients with severe burns

作　　者：王雪欣 张明谏[2] 李小兵[2] 

机构地区：[1]天津医科大学一中心临床学院,300070 [2]天津市第一中心医院整形与烧伤外科

出　　处：《中华烧伤杂志》2018年第1期57-59,共3页Chinese Journal of Burns

摘　　要：严重烧伤患者伤后微量元素含量均不同程度下降，锌缺乏一直是该领域的研究热点。肠内外营养制剂的普遍应用丰富并均衡了人体所需的各种营养成分，但是其中锌等微量元素的含量仅能满足人体的基本生理需要，远低于严重烧伤患者的需要量；另外，锌含量的监测也尚未被广泛应用于临床以指导严重烧伤患者的补锌治疗。本文对锌的生理功能和代谢平衡，严重烧伤患者锌含量的测定及锌缺乏的原因和影响，补锌治疗的作用、方法和剂量等进行综述。Zinc is one of the essential trace elements in human body, which plays an important role in regulating acute inflammatory response, glucose metabolism, anti-oxidation, immune and gastrointestinal function of patients with severe burns. Patients with severe burns may suffer from zinc deficiency because of insufficient amount of zinc intake from the diet and a large amount of zinc lose through wounds and urine. Zinc deficiency may affect their wound healing process and prognosis. This article reviews the characteristics of zinc metabolism in patients with severe burns through dynamic monitoring the plasma and urinary concentration of zinc. An adequate dosage of zinc supplemented to patients with severe burns by an appropriate method can increase the level of zinc in plasma and skin tissue and improve wound healing, as well as reduce the infection rates and mortality. At the same time, it is important to observe the symptoms and signs of nausea, dizziness, leukopenia and arrhythmia in patients with severe burns after supplementing excessive zinc.

关 键 词：烧伤 锌 锌缺乏 补锌治疗 

分 类 号：R644[医药卫生—外科学]