抗菌素联合妇乐片强化巩固方案治疗盆腔炎性疾病的临床观察  

Clinical Observation of Intensive Treatment with Antibiotics and Chinese Medicine Fule Tablets for Treatment of Pelvic Inflammatory Disease

作　　者：张丽卿[1] 戚潜辉[1] 周龙书[1] 

机构地区：[1]广州医科大学附属第二医院,广东广州510260

出　　处：《广州中医药大学学报》2018年第1期19-23,共5页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：广东省中医药局立项课题(编号:20072106)

摘　　要：【目的】探讨抗菌素联合妇乐片强化巩固方案治疗盆腔炎性疾病(PID)的近期疗效。【方法】将240例PID患者随机分为观察组和对照组,每组各120例。观察组给予抗菌素(金汕秦或世福素+奥硝唑)14 d(d1-d14)+妇乐片30 d(d1-d30)治疗,对照组仅予抗菌素(金汕秦或世福素+奥硝唑)14 d(d1-d14)治疗。观察2组患者在治疗后7 d、14 d和30 d的下腹痛(VAS评分)、子宫压痛或附件区压痛、体温、阴道分泌物、B超检查情况,并评价其疗效。【结果】(1)观察指标方面:治疗后,2组下腹痛VAS评分、子宫压痛或附件区压痛、发热、阴道分泌物异常、盆腔积液和附件增粗或包块等均较治疗前明显改善(P<0.05),且观察组在第30天对下腹痛VAS评分、子宫压痛或附件区压痛、阴道分泌物异常和盆腔积液的改善作用均明显优于对照组,差异有统计学意义(P<0.05)。(2)疗效方面:在治疗后7 d、14 d,2组疗效比较差异无统计学意义(P>0.05),但在治疗后30 d,观察组疗效优于对照组,差异有统计学意义(P<0.05)。【结论】妇乐片联合抗菌素强化巩固方案治疗PID的疗效优于单纯抗菌素治疗,可有效改善临床证候,缩短病程,减少或预防后遗症的发生。Objective To investigate the short-term clinical effect of intensive treatment with antibiotics and Chinese medicine Fule Tablets for pelvic inflammatory disease（PID）. Methods A total of 240 PID patients were randomly divided into observation group and control group,120 cases in each group. The observation group was given oral use of antibiotics（Cefodizime or Cefixime Granules ＋ Ornidazole） for 14 days（d1-d14） and Fule Tablets orally for 30 days（d1-d30）. The control group was only given oral use of antibiotics（Cefodizime or Cefixime Granules ＋ Ornidazole）for 14 days（d1-d14）. Visual Analogue Scale（VAS）scores for lower abdominal pain,tenderness of the uterus or adnexal region, body temperature, vaginal secretions, and ultrasonogram were observed after treatment for 7, 14 and 30 days in both groups. And the therapeutic effect was also evaluated.Results（1） After treatment,VAS scores for lower abdominal pain,tenderness of the uterus or adnexal region,fever, vaginal secretions, pelvic hydrops, adnexal thickening or adnexal mass in the two groups were much improved after treatment（P 0.05 compared with those before treatment）,and the improvement of VAS scores for lower abdominal pain,tenderness of the uterus or adnexal region,vaginal secretions,and pelvic hydrops in the observation group on day 30 was superior to that in the control group（P 0.05）.（2）After treatment for7,14 days,the differences of the therapeutic effect between the two groups were insignificant（P 0.05）. After treatment for 30 days,the therapeutic effect of the observation group was much stronger than that in the control group（P 0.05）. Conclusion The intensive treatment with antibiotics and Chinese medicine Fule Tablets has stronger effect for the treatment of PID than antibiotics alone,which is effective on relieving clinical symptoms and signs,shortening the course of disease,and reducing or preventing the occurrence of sequelae.

关 键 词：妇乐片 抗菌素 盆腔炎性疾病 

分 类 号：R271.9[医药卫生—中西医结合] R711.33[医药卫生—中医妇科学]