分化型甲状腺癌患者^(131)I治疗后大量饮水开始时间的研究  

An analysis of influence of drinking plenty of water at different time in differentiated thyroid carcinoma patients after ^(131)I treatment on the equivalent dose rate

作　　者：易于颦[1] 朱玉泉[1] 段东[1] 胡凤琼[1] 

机构地区：[1]重庆市重庆医科大学附属第一医院核医学科,400016

出　　处：《中华护理杂志》2018年第1期8-11,共4页Chinese Journal of Nursing

摘　　要：目的探讨分化型甲状腺癌患者^(131)I治疗后大量饮水开始时间。方法将83例分化型甲状腺癌患者随机分为A、B、C组,分别予^(131)I治疗后12 h(A组)、24 h(B组)、36 h(C组)开始大量饮水,采用γ射线监测仪分别测量并比较3组服用^(131)I后6 h、12 h、24 h、36 h、48 h、72 h距离患者腹部及颈部1 m处辐射当量剂量率;比较3组各时间点可以出院患者例数并评价其疗效。结果 3组服用^(131)I后24 h和36 h腹部当量剂量率及服用^(131)I后36 h及48 h可出院患者例数不同,差异均有统计学意义(P<0.05);3组^(131)I治疗疗效比较,差异无统计学意义(P>0.05)。结论分化型甲状腺癌患者^(131)I治疗后12 h开始大量饮水可在保证疗效的前提下,加速降低患者早期周围辐射当量剂量率,缩短患者住院隔离时间。Objective To explore the optimal time for starting to drink plenty of water after ^131I treatment in dif- ferentiated thyroid carcinoma（DTC） patients. Methods Totally 83 cases of DTC patients were randomly divided in- to three groups,and started to drink plenty of water at 12 h（group A）,24 h（group B）,and 36 h（group C） after treatment with ^131I therapy. We measured and compared equivalent dose rate using the Inspector Alert gamma ray monitor at 1 meter in front of the patient＇s ahdomen and neck at 6 h,12 h,24 h,36 h,48 h,72 h after taking ^131I. We compared the discharge rate at different time and evaluated the curative effect. Results Equivalent dose rate of the abdomen at 24 h and 36 h after treatment and the discharge rate at 36 h and 48 h after treatment among three groups showed significant differences（P〈0.05）. There were no statistically significant differences in the cura- tive effect（P〉0.05）. Conclusion Starting to drink plenty of water at 12 h after taking ^131I can accelerate the decreas- ing of equivalent dose rate with no influence on the curative effect and improve the discharge rate at early.

关 键 词：甲状腺肿瘤 当量剂量率 ^131I 饮水 

分 类 号：R473.73[医药卫生—护理学]