西安地区43家基层医院2013-2015年质子泵抑制剂使用现状调查分析  

ClinicaL APPLICATION ANALYSIS OF PROTON PUMP INHIBITORS IN 43 HOSPitals of Xi'an during 2013-2015

作　　者：张桂贞[1] 李海燕[1] 韩晶[2] 胡斌[1] 

机构地区：[1]西安市第四医院药剂科,陕西西安710004 [2]西安交通大学医学院公共卫生学系地方病研究所/环境与疾病相关基因教育部重点实验室,陕西西安710061

出　　处：《西部医学》2018年第1期137-140,共4页Medical Journal of West China

基　　金：陕西省自然科学青年项目(2015JQ8310)

摘　　要：目的调查西安地区基层医院质子泵抑制剂(PPIs)使用现状,为促进制定合理用药政策提供决策依据。方法对西安地区43家二级医院2013-2015年PPIs销售总金额、PPIs所占金额比、PPIs单品种销售金额、用药频度(DDDs)、日均费用(DDC)等数据进行统计分析。结果 43家医院使用PPIs品种较固定,销售金额、PPIs所占金额比呈逐年上升趋势。三年中每年PPIs占药品总金额比率分别为2.18%、2.50%和2.75%。静脉制剂中泮托拉唑、奥美拉唑、口服制剂中奥美拉唑销售金额稳居前3位,3种PPIs总金额构成比均在65%以上,是临床使用量较大的品种。结论43家医院PPIs销售金额和用量增长较快都有。但临床治疗中仍应关注质子泵抑制剂的合理使用,加强监管避免其滥用和过度使用。Objective To investigate the utilization of proton pump inhibitors （PPIs） in the hospitals from Xi＇an, and to provide reference for rational use of PPIs. Methods The utilization of PPIs in 43 secondary hospitals from Xi＇an during 2013-2015 was statistically analyzed with respects of total consumption sum of PPIs, the proportion of PPIs sum, the consumption sum, DDDs and DDC of each PPIs. Results The total consumption sum and the proportion of PPIs sum increased year by year from 2013 to 2015. And the proportion of PPIs sum was 2.18%, 2.50% and 2.75% respectively. Omeprazole and pantoprazole for injection,oral dosage forms of omeprazole took up the top three in the list of consump- tion sum,and took up 65% of the consumption sum in the 3 years. Conclusion At present,the consumption sum and a- mount of PPIs is rapidly increasing. Great importance should be attached to the rational administration and safety use of the PPIs,in order to avoid excess use.

关 键 词：质子泵抑制剂 合理用药 销售金额 用药频度 日均费用 

分 类 号：R943[医药卫生—药剂学]