慢性化脓性中耳炎病原菌分析及临床意义  

Pathogen analysis and clinical significance in chronic suppurative otitis media

作　　者：李明[1] 廖剑绚[1] 沈宝茗[1] 江青山[1] 刘洁[1] 

机构地区：[1]南华大学附属第一医院耳鼻咽喉科,湖南衡阳421001

出　　处：《中国耳鼻咽喉颅底外科杂志》2017年第6期563-565,共3页Chinese Journal of Otorhinolaryngology-skull Base Surgery

摘　　要：目的分析慢性化脓性中耳炎患者病原菌群分布及对抗生素的耐药性,指导临床用药。方法对收治的163例慢性化脓性中耳炎患者中耳分泌物进行细菌及真菌分离培养和药物敏感试验。结果 163例患者中,有136例检出病原菌,检出率为83.4%。以金黄色葡萄球菌(42株)、铜绿假单胞菌(29株)和肺炎克雷伯菌(22株)为主,真菌6株。结论慢性化脓性中耳炎患者感染病原菌中以金黄色葡萄球菌多见,不同病原菌对药物的耐药性不同,临床使用抗生素时应行细菌培养及药物敏感试验,使用敏感抗生素治疗。Objective To study the flora distribution and the resistance to antibiotics of pathogenic bacteria in chronic suppurative otitis media for instruction of clinical medication. Methods Middle ear secretions from 163 cases with chronic suppurative otitis media were cultured for bacteria and fungi respectively. Antimicrobial sensitivity tests were also performed. Results 136 strains pathogenic bacteria were isolated from the secretions with a detection rate of 83.4% （ 136/ 163）. The main pathogenic bacteria were staphylococcus aureus （42 strains ）, pseudomonas aeruginosa （ 29 strains）, Klebsiella pneumoniae （22 strains） and fungus （6 strains）. Conclusions Staphylococcus aureus is the main pathogen of chronic suppurative otitis media. There are great differences in resistances among different pathogens. In the clinical treatment of chronic suppurative otitis media, bacterial culture and antimierobial sensitivity test should be performed, and sensitive antibiotics should be chosen according to the results.

关 键 词：中耳炎 化脓性 细菌培养 药敏实验 

分 类 号：R764.21[医药卫生—耳鼻咽喉科]