1例起搏器术后房颤伴右心衰患者停用β受体阻滞剂的分析  

Analysis A Case of Patient with Atrial Fibrillation and Right Heart Failure after Pacemaker Postoperative Stoped Beta Blockers

作　　者：杨建良[1] 谢群坚[1] 刘小畅[2] 

机构地区：[1]广州市胸科医院药剂科,广东广州510095 [2]广东省人民医院珠海医院,珠海市金湾中心医院,广东珠海519040

出　　处：《今日药学》2017年第12期839-840,844,共3页Pharmacy Today

摘　　要：β受体阻滞剂可减慢心率、降低心肌耗氧量、抑制肾素-血管紧张素-醛固酮系统(RAAS)、延缓心肌重构、提高左心室的射血分数(LVEF)、改善患者长期预后,是治疗心衰的基石药物。但对于心脏射血分数(EF)保留的心衰和右心衰,β受体阻滞剂的获益则尚不明确。且对植入起搏器患者的用药更应结合其自身情况分析利弊。临床药师关注医生容易忽略的药物相互作用问题,提供药学服务等,减少或避免了中毒不良事件的发生,保障安全有效的药物治疗。临床药师在临床药物治疗实践中积累药物使用和药学监护经验,并体现临床药师的价值。Beta-blocker is the basal drug for the treatment of heart failure patients. It can reduce the heart rate and myocardial oxygen, inhibit RAAS, delay myocardial remodeling, improve LVEF and the long-term prognosis of patients. But for the right heart failure with EF reserves, the benefit of the beta-blockers was unclear. Especially in patients with implanted pacemaker that should be combined situation to analysis. Clinical pharmacists paid attention to the question of drug interactions that doctors ignored and provided pharmaceutical care for doctors. It can also be decreased or prevented incidence rate of adverse events and guarantee a safe and effective medication. The clinical pharmacists also accumulated experience in the pharmaceutical care of patients and exemplified the values of clinical pharmacists.

关 键 词：右心衰 房颤 Β受体阻滞剂 

分 类 号：R969.4[医药卫生—药理学]