维生素A水平与儿童呼吸道感染性疾病的相关性研究  

The Study of the Correlation between Vitamin A Levels and Infectious Diseases in Children

作　　者：李延琪 杨拴盈[1] 

机构地区：[1]西安交通大学第二附属医院呼吸内科,陕西西安710004 [2]西安市儿童医院,陕西西安710004

出　　处：《吉林医学》2018年第1期3-5,共3页Jilin Medical Journal

基　　金：国家卫生计生委专项基金[项目编号:W2015EAE055]

摘　　要：目的:研究血清维生素A缺乏水平与儿童反复呼吸道感染和儿童急性支气管肺炎的疾病影响情况及相关性分析。方法:选取1 630例患儿纳入研究,分为反复呼吸道感染(RRI)组、支气管肺炎(BP)组及对照组。观察比较三组患儿的形态学以及检测血清维生素A的浓度水平变化。结果:三组患儿在一般形态学(年龄、性别、身高、体重、居住地)方面的比较,差异无统计学意义(P>0.05);所有病例中男童血清VA水平与女童血清VA水平的比较,差异无统计学意义(P>0.05);三组患儿血清维生素A浓度检测结果的差异有统计学意义(P<0.05);两组病例组中VAD、SVAD总检出率分别为15.7%、39.8%,均明显高于对照组的5.6%、20.6%,差异有统计学意义(P<0.05)。结论:维生素A与儿童呼吸道感染关系密切,儿童反复呼吸道感染和支气管肺炎患儿中普遍存在维生素A缺乏,且慢性感染(反复呼吸道感染)比急性感染(支气管肺炎)的维生素A缺乏更为明显。Objective To study the effects of serum vitamin A deficiency in children with recurrent respiratory tract infections and acute bronchial pneumonia. Method In all of 1 630 cases,the patients were divided into recurrent respiratory tract infection（RRI） group,bronchial pneumonia（BP） group and control group. The morphology of the three groups of children and the changes in serum levels of vitamin A were observed. Results There was no statistically significant difference in the general morphology（age,sex,height,weight,residence） of the three groups（P〈0. 05）. There was no statistically significant difference between serum VA level of boys and girls in all cases（P〈0. 05）. The differences in serum vitamin A concentration were statistically significant（P〈0. 05）. The total detection rate of VAD and SVAD in both groups was 15. 7% and 39. 8%,respectively,which was significantly higher than 5. 6% and 20. 6% of the control group,and the difference was statistically significant（P〈0. 05）. Conclusion Vitamin A is closely related to respiratory infection in children. Vitamin A deficiency is common in children with recurrent respiratory tract infections and bronchial pneumonia. The vitamin A deficiency of chronic infections（recurrent respiratory tract infections） are more obvious than acute infections（Bronchial pneumonia）.

关 键 词：维生素A 亚临床缺乏 反复呼吸道感染 支气管肺炎 

分 类 号：R725.6[医药卫生—儿科]