自拟补肾调经汤辅助治疗肾虚血瘀型多囊卵巢综合征不孕的疗效及对激素水平的影响  

Effect of Bushen Tiaojing Decoction assisted in treating infertility caused by polycystic ovary syndrome with kidney deficiency and blood stasis and its effect on hormone level

作　　者：郑苏娟 徐颖[1] 

机构地区：[1]中国人民解放军第四七六医院妇产科,福建福州350001

出　　处：《中国计划生育和妇产科》2018年第1期63-66,共4页Chinese Journal of Family Planning & Gynecotokology

摘　　要：目的探究自拟补肾调经汤辅助治疗肾虚血瘀型多囊卵巢综合征(polycystic ovary syndrome,PCOS)不孕的临床效果及对激素水平影响。方法选择2013年7月至2016年2月于中国人民解放军第四七六医院诊治的87例肾虚血瘀型PCOS不孕患者,按随机数字表法分为研究组44例和对照组43例。对照组予常规西医药物治疗,研究组加用自拟补肾调经汤治疗。比较两组临床中医症状积分、血清激素水平变化、影像学变化、临床疗效。结果治疗后两组头晕耳鸣、性欲减退、腰膝酸软、腰腹刺痛、痛经且经血含血块五项中医症状均较治疗前明显改善,且研究组改善更大,差异有统计学意义(P<0.05);治疗后两组的血清瘦素、雌二醇、黄体生成素、睾酮水平均低于治疗前,且研究组下降更明显,差异有统计学意义(P<0.05);治疗后两组的子宫体积明显大于治疗前,而卵巢体积明显小于治疗前,且研究组治疗后的子宫体积大于对照组、卵巢体积小于对照组,差异均有统计学意义(P<0.05);研究组的中医治疗总有效率、妊娠率均高于对照组,差异有统计学意义(P<0.05)。结论自拟补肾调经汤辅助用药可改善肾虚血瘀型PCOS不孕患者的不良症状,降低激素水平,改善子宫、卵巢状况,提高妊娠率。Objective To investigate the clinical effect of Bushen Tiaojing Decoction in adjuvant treatment of infertility with polycystic ovary syndrome （PCOS） and its effect on hormone levels. Methods 87 cases of PCOS infertility patients with deficiency of kidney and blood stasis diagnosed and treated in the 476th Hospital of People＇s Liberation Army from July 2013 to February 2016 was divided into study group （44 cases） and control group Group of （43 cases）. Patients in the control group were treated by routine western medicine, while the study group was treated with Bushen Tiaojing decoction and routine western medicine. Compared the changes of TCM symptom score, serum hormone level, imaging index and clinical efficacy of the two groups. Results After treatment, the TCM symptom scores （tinnitus and dizziness, loss of libido, weak waist, waist pain, dysmenorrhea and containing blood clot） in the two groups improved obviously compared to before treatment （P 〈 0.05 ）; After treatment, the levels of serum leptin, estradiol, luteinizing hormone and testosterone in the two groups were lower than those before treatment （P 〈 0.05） ; After treatment, the volume of the uterus in the two groups was obviously larger than that before the treatment, and the volume of the ovary was significantiy lower than that before the treatment, while the volume of uterus after treatment in the study group was larger than that of the control group and the volume of the ovary was less than that of the control group. The differences were statistically significant （P 〈 0.05） ; The study group＇s total effective rate of TCM treatment and pregnancy rate were higher than the control group, the difference was statistically significant （ P 〈 0. 05 ）. Conclusion The Bushen Tiaojing decoction can improve the symptoms of patients with adjuvant PCOS infertility with kidney deficiency and blood stasis, reduce hormone levels, improve uterine and ovarian status and increase pregnancy rate.

关 键 词：补肾调经汤 多囊卵巢综合征 肾虚血瘀型 激素 疗效 

分 类 号：R711.75[医药卫生—妇产科学]