微环境对干细胞向心肌细胞分化影响的研究进展  

Advances in research on the effects of microenvironment on the differentiation of stem cells into cardiomyocytes

作　　者：田琨 穆军升[1] 

机构地区：[1]首都医科大学附属北京安贞医院心外科,100029

出　　处：《中华胸心血管外科杂志》2017年第12期764-768,共5页Chinese Journal of Thoracic and Cardiovascular Surgery

摘　　要：微环境对干细胞的分化有着重要影响.通过控制微环境来实现干细胞定向分化,比传统诱导法更接近实际生理特性,无疑具有更为广阔的临床应用前景.本文对微环境对干细胞向心肌细胞分化影响的研究进展作一综述.Microenvironment has a major impact on stem-cell differentiation. Stem-cell differentiation achieved by controlling the microenvironment is more similar to physiological characteristic than the traditional chemical induction, which will undoubtedly have a broader clinical application prospect. The impact of microenvironment on stem cell to cardiomyocyte differentiation is reviewed in this paper.

关 键 词：心肌细胞分化 微环境 干细胞 细胞定向分化 生理特性 临床应用 诱导法 

分 类 号：R54[医药卫生—心血管疾病]