探讨解脲脲支原体或沙眼衣原体感染与复发性自然流产的相关性  

Correlation between Ureaplasma urealyticum and Chlamydia trachomatis infections and recurrent spontaneous abortion

作　　者：邢娴静 陈燕娥[1] 吴学明[1] 陈绵[1] 唐海妹[1] 曾蕾 

机构地区：[1]海口市妇幼保健院妇科,海南海口570100

出　　处：《中华医院感染学杂志》2018年第2期254-256,268,共4页Chinese Journal of Nosocomiology

摘　　要：目的探讨和分析解脲脲支原体(UU)、沙眼衣原体(CT)感染与复发性自然流产的相关性。方法选取2014年1月-2016年12月期间医院收治的250例自然流产(其中包括复发性自然流产81例)孕妇作为研究组,另选取250例同期在医院自愿进行人工流产的正常孕妇作为对照组,比较两组研究对象宫颈分泌物、蜕膜组织中UU和CT感染情况,分析复发性与非复发性自然流产患者宫颈分泌物中、蜕膜组织中UU和CT感染检测情况。结果研究组孕妇宫颈分泌物中UU阳性率38.80%(97/250),CT阳性率29.20%(73/250),UU+CT阳性率24.00%(60/250)均高于对照组(P<0.05);复发性自然流产患者宫颈分泌物中UU阳性率82.71%(67/81),CT阳性率65.43%(53/81),UU+CT阳性率51.85%(42/81)均高于非复发性自然流产孕妇(P<0.05);研究组患者蜕膜组织中UU阳性率35.20%(88/250),CT阳性率28.80%(72/250),UU+CT阳性率20.40%(51/250)均高于对照组(P<0.05);复发性自然流产患者蜕膜组织中UU阳性率77.78%(63/81),CT阳性率60.49%(49/81),UU+CT阳性率43.21%(35/81)均高于非复发性自然流产孕妇患者(P<0.05)。结论 UU、CT感染与复发性自然流产之间存在密切关系,通过对UU、CT感染的检测可以有效预防复发性自然流产的发生。OBJECTIVE To explore the relationship between the Ureaplasma urealyticum（UU）and Chlamydia trachomatis（CT）infections and the recurrent spontaneous abortion.METHODS A total of 250 pregnant women who had spontaneous abortion（including 81 cases of recurrent spontaneous abortion）and were treated in the hospital from Jan 2014 to Dec 2016 were selected as the study group,meanwhile,250 normal pregnant women who underwent voluntary induced abortion were set as the control group.The prevalence rates of UU and CT infections in cervical secretions and decidual tissues were compared between the two groups of study objects,and the positive rates of UU and CT in cervical secretions and decidual tissues were observed and compared between the recurrent spontaneous abortion patients and the non-recurrent spontaneous abortion patients.RESULTS The positive rates of UU,CT and UU plus CT were respectively 38.80%（97/250）,29.20%（73/250）and 24.00%（60/250）in the cervical secretions of the pregnant women in the study group,higher than those in the control group（P〈0.05）.The positive rates of UU,CT and UU plus CT in the cervical secretions of the recurrent spontaneous abortion patients were respectively 82.71%（67/81）,65.43%（53/81）and 51.85%（42/81）,higher than those of the non-recurrent spontaneous abortion patients（P〈0.05）.The positive rates of UU,CT and UU plus CT in the decidual tissues were respectively 35.20%（88/250）,28.80%（72/250）and 20.40%（51/250）in the study group,higher than those in the control group（P〈0.05）.The positive rates of UU,CT and UU plus CT in the decidual tissues of the recurrent spontaneous abortion patients were respectively 77.78%（63/81）,60.49%（49/81）and 43.21%（35/81）,higher than those of the non-recurrent spontaneous abortion patients（P〈0.05）.CONCLUSION The UU and CT infections are closely associated with the recurrent spontaneous abortion,and the detection of UU and CT infection may contribute to the effective prevention of the recurr

关 键 词：自然流产 解脲脲支原体 沙眼衣原体 感染 

分 类 号：R714.21[医药卫生—妇产科学]