干酪乳杆菌的免疫及其作为载体的应用研究进展  

Progress on Immunization of Lactobacillus casei and Its Application as A Vector

作　　者：刘欢欢 李树东[1] 王珊珊[1] 高国强[1] 余丽芸[2] 侯喜林[1] 

机构地区：[1]黑龙江八一农垦大学动物科技学院,黑龙江大庆163319 [2]黑龙江八一农垦大学生命科技学院,黑龙江大庆163319

出　　处：《动物医学进展》2018年第2期96-101,共6页Progress In Veterinary Medicine

基　　金：黑龙江省高校产业化前期培育项目(1253CGZH14);黑龙江省农垦总局科技攻关项目(HNK135-04-06)

摘　　要：干酪乳杆菌是公认的保健类肠道益生菌,能在肠道内长期存在并诱发机体的先天性和特异性免疫应答。它作为一种新型疫苗的抗原递呈载体与传统的载体相比,可以诱导产生更强烈的肠道黏膜免疫应答。论文综述了干酪乳杆菌作为抗原递呈载体的国内外最新研究进展,阐述其作为抗原递呈载体的应用价值,为相关研究提供借鉴。Lactobacillus casei is a kind of recognized healthy intestinal probiotic. It can exist in the intestinaltract for a long time and induce the innate and specific immune responses. As an antigen presenting vectorfor novel vaccines,it can reduce intestinal mucosal immune response more strongly than previous vectors.In this article, some researches on L. casei as antigen presenting vectors and its application value were sum-marized for providing some references for relevant research.

关 键 词：干酪乳杆菌 免疫应答 抗原递呈载体 

分 类 号：S852.612[农业科学—基础兽医学]