半枝莲方治疗银屑病血热证的临床观察  

Effect of Banzhilian Decoction(半枝莲方) on Psoriasis Vulgaris Patients with Blood-heat Syndrome

作　　者：刘勇[1] 孙丹 闫小宁 

机构地区：[1]陕西中医药大学 [2]陕西省中医医院,陕西西安710004

出　　处：《中医药导报》2018年第2期81-83,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：陕西省科学技术厅支持项目(2016LCZX-12);陕西省科学技术厅支持项目(2015HM-13)

摘　　要：目的:观察半枝莲方治疗银屑病血热证的疗效。方法:采用随机对照分组法,将75例寻常型银屑病血热证患者分为3组。治疗组25例,予半枝莲方口服联合卡泊三醇乳膏外用治疗;对照1组25例,给予卡泊三醇乳膏外用;对照2组25例,给予半枝莲方口服。于治疗前后分别对3组患者皮损进行真菌培养、同时进行PASI评分及中医证候评分,4周后观察3组患者临床疗效。结果:治疗后3组PASI评分、中医证候评分较前均有改善(P<0.05);治疗后治疗组与对照1组PASI评分、中医证候评分及真菌培养阴性率比较,差异均有统计学意义(P<0.05);治疗后治疗组与对照2组PASI评分、中医证候评分及真菌培养阴性率比较,差异均无统计学意义(P>0.05)。治疗组愈显率为88.0%,对照1组为48.0%,对照2组为76.0%,治疗组与对照1组比较,差异有统计学意义(P<0.05);与对照2组比较,差异无统计学意义(P>0.05)。结论:半枝莲方可能通过降低皮损真菌感染率而达到治疗血热证银屑病的效果。Objective： To observe the clinical curative effect of Banzhilian decoction （半枝莲方, BZLD） on psoriasis patients with blood heat syndrome. Methods： 75 patients with psoriasis vulgaris were divided into three groups by randomized controlled grouping. 25 cases of treatment group were treated with BZLD combined with topical cream, 25 cases of control group 1 were treated with topical cream, 25 cases of control group 2 were treated with BZLD. The lesions of the three groups were treated with fungus culture before and after treatment, and the PASI and TCM syndromes were scored at the same time. After 4 weeks, the clinical curative effect of the three groups was observed. Results： After treatment, the scores of PASI and TCM syndromes of the three groups were improved （P〈0.05）. After treatment, the scores of PASI, TCM syndromes and negative rate of fungal culture were significantly different between the treatment group and the control group 1 （P〈0.05）. There was no significant difference in PASI score, TCM syndromes score and fungus culture negative rate between treatment group and control group2 after treatment （P〉0.05）. The effective rate was 88.0% in the treatment group, 48.0% in the control group 1 and 76.0% in the control group 2, the difference between the treatment group and the control group 1 was statistically signifieant （P〈0.05）; compared with the control group 2, there was no significant difference （P〉0.05）. Conclusion： BZLD could reduce the incidence of fungal infection of skin lesions and achieve the curative effect of treating psoriasis of blood heat syndrome.

关 键 词：银屑病 血热证 半枝莲方 糠秕孢子菌 

分 类 号：R275[医药卫生—中医皮科]