Isatindigodiphindoside,an alkaloid glycoside with a new diphenylpropylindole skeleton from the root of Isatis indigotica  

作　　者：Ling-Jie Meng Qing-Lan Guo Cheng-Gen Zhu Cheng-Bo Xu Jian-Gong Shi 

机构地区：[1]State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sdences and Peking Union Medical College, Belting 100050, China

出　　处：《Chinese Chemical Letters》2018年第1期119-122,共4页中国化学快报（英文版）

基　　金：Financial support from the National Natural Science Foundation of China(Nos. 81373287, 81630094 and 30825044)

摘　　要：A novel indole alkaloid glycoside with an unprecedented 2-（diphenylpropyl）indole skeleton, isatindigodiphindoside （1）, was isolated from an aqueous extract of the roots of lsatis indigotica. The structure was determined by extensive spectroscopic studies, especially by 2D NMR data analysis combined with enzymatic hydrolysis and ECD calculations. Plausible biosynthetic pathways of compound 1 are also discussed.A novel indole alkaloid glycoside with an unprecedented 2-（diphenylpropyl）indole skeleton, isatindigodiphindoside （1）, was isolated from an aqueous extract of the roots of lsatis indigotica. The structure was determined by extensive spectroscopic studies, especially by 2D NMR data analysis combined with enzymatic hydrolysis and ECD calculations. Plausible biosynthetic pathways of compound 1 are also discussed.

关 键 词：CruciferaeIsatis indigoticaBan lan genDiphenylpropylindoleAlkaloid glycosidelsatindigodiphindoside 

分 类 号：O6[理学—化学]