一步合成花朵形状的Au纳米结构以及在电化学测定多巴胺方面的应用  

One-step synthesis of flower-shape Au nanostructures and their application in dopamine sensing

作　　者：张燕[1] 宋雪晶[1] 陈妹琼[1] 蔡志泉[1] 张敏 程发良 

机构地区：[1]东莞理工学院城市学院,东莞523419 [2]广东省新型纳米材料工程技术研究中心,东莞523808

出　　处：《分析试验室》2018年第2期141-145,共5页Chinese Journal of Analysis Laboratory

基　　金：国家自然科学基金(21375016;21475022;21505019);广东省自然科学基金(2015A030310272);广东省科技计划项目(2015B090927007);广东省重点平台与高校重大科研项目(2014KZDXM073;2014KTSCX181;2015KCXTD029;2016KQNCX219);广东省高等学校学科与专业建设专项资金(2013LYM_0105);东莞市社会科技发展一般项目(2017507151065)资助

摘　　要：通过水热法在导电玻璃表面一步合成花朵形状Au纳米结构。以此花朵形状Au纳米结构修饰电极为工作电极来组装多巴胺传感器;电化学数据显示花朵形状Au纳米结构能够加速电子在多巴胺和电极表面传递,减少电化学氧化过程中的过电位,多巴胺的浓度在1.25μmol/L^1.07 mmol/L范围内,氧化峰电流与浓度存在线性关系(R=0.997),检测限为0.61μmol/L。合成的电化学传感器具有良好的稳定性和重复性,为多巴胺的实际分析检测提供了一种新方法。Noble metal nanomaterials attract considerable attention due to their larger surface area, excellent conductivity, desirable biological compatibility as well as good stability, which has been extensively applied to catalysis, analysis and biosensor fields. We have synthesized a novel flower-shape Au nanostructure on ITO surface by one-step hydrothermal reaction via adjusting reaction temperature. We further investigated the electrochemical application of flower-shape Au nanostructure in constructing dopamine sensor. The results showed that dopamine sensor exhibits a wide linear range from 1.25 μmol/L to 1. 07 mmol/L （ R = 0. 997 ）, and the detection limit is estimated to be 0. 61 μmol/L （S/N = 3 ）. Moreover, dopamine sensor has good selectivity, stability and repeatability. These results indicate that the flower-shape Au nanostructure-based sensor provides a novel method for the real application of the dopamine detection.

关 键 词：电化学传感器 花朵形状Au纳米结构 多巴胺 

分 类 号：R917[医药卫生—药物分析学]