中西医结合治疗乙型肝炎病毒慢加急性肝衰竭临床研究  

A clinical study on treating HBV-ACLF in the integrative medicine

作　　者：杜洪波[1] 房阳[1] 吴婷婷 高辉[1] 田爱华[1] 

机构地区：[1]齐齐哈尔市第一医院,黑龙江齐齐哈尔161000

出　　处：《中医临床研究》2017年第34期14-16,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的:观察中西医结合疗法对乙型肝炎病毒(HBV)慢加急性肝衰竭(ACLF)的临床疗效。方法:将200例乙型肝炎病毒慢加急性肝衰竭患者随机分为对照组(80例,常规西医治疗)和观察组(120例,在对照组基础上联合凉血解毒化癖法辨证用药),均治疗8周。检测治疗前,治疗第4周及第8周时血清总胆红素(TBIL)、直接胆红素(DBIL)、血清丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、白蛋白(ALB)、胆碱酯酶(Ch E)和凝血酶原活动度(PTA)、国际标准化比值(INR)的水平。结果:两组治疗后ALT、TBIL降低,ALB、PTA升高,差异有统计学意义(P<0.05);第4周时两组间TBIL、DBIL、PTA差异有统计学意义(P<0.05),8周时两组间TBIL、ALT、AST、ALB、PTA、INR差异均有统计学意义(P<0.05)。结论:中西医结合治疗乙型肝炎病毒慢加急性肝衰竭可以取得更加明显的临床疗效,且随着治疗时间的延长,治疗效果更加明显。Objective： To observe the clinical efect of the integrative medicine on hepatitis B virus related-acute-on-cohronic liver failure. Methods： 200 patients were randomly divided into the control group （80 cases, conventional western medicine treatment） and observation group （120 cases, the Liangxue Jiedu Huapi therapy more）, and treated for 8 weeks. Results： After treatment, ALT, TBIL were decreased; ALB and PTA were increased; the difference was statistically significant （P〈0.05）; the difference of TBIL, DBIL and PTA between groups at the 4th week were statisically signifcant （P〈0.05）. There were signifcant diferences in TBIL, ALT, AST, ALB, PTA and INR between the groups at 8th week （P〈0.05）. Conclusion： The combination treatment for hepatitis B virus acute liver failure can achieve more obvious clinical efcacy.

关 键 词：中西医结合 乙型肝炎病毒 慢加急性肝衰竭 治疗 

分 类 号：R512.61[医药卫生—内科学]